Does anyone have knowledge about the suc... - Early CKD Support

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Does anyone have knowledge about the success/longevity of kidney transplants once diagnosed with rapid onset IgA nephropathy plse?

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buryboy

Depends if it's from a living donor or not if I remember correctly it's about 15 years

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outlook

Thank you. It would be living donor -- but why would this make a difference regarding recurrence of IgA?

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googie

I think what buryboy is saying that a kidney lasts around 15 years once transplanted. If you had a new kidney would it recurr?? or is that what you are asking? If so, I found this info from:

unckidneycenter.org/kidneyh...

Will the IgA nephropathy come back in my kidney transplant?

A return of this disease is fairly common after a kidney transplant. If you did a kidney biopsy of all transplant patients with IgA nephropathy, about 60% of them would have evidence of the disease in the biopsy sample. But not all would have symptoms or other abnormal test results. About 20-40% of patients actually have abnormal protein or blood detected in their urine due to a return of the disease.

Recurrence usually happens, on average, around 2.5 years after the transplant. But it can occur at any time.

Is there any treatment for IgA nephropathy that comes back in a transplant?

There are no specific treatments for this disease in transplant patients. The treatment is similar to the treatment of the disease in your original kidneys. This includes blood pressure control and immunosuppressive medications for more severe cases.

If the IgA nephropathy does come back, will it cause me to lose my kidney transplant?

Fortunately, renal function is usually good for several years after recurrence of IgA in a transplant. After about 5 years, the rate of kidney loss due to the disease is increased. About 40% of patients who have recurrent IgA will eventually lose their kidney because of the disease. However, it can take up to 10 years or more for that to happen.

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outlook in reply to googie

Many thanks, this is hepful. I was also wondering whether if you are diagnosed with rapid onset of IgAN, you will more likely get "rapid return" (so to speak) in the new kidney,rather than the more gradual recurrence.

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googie

oooh not sure, but as they know about the rapid onset, would they have a plan already in place in order to maybe slow it down?