This study was designed to see if lowering A1c to 6.5%, instead of the ADA's recommended 7.0%, could prevent heart attacks. The study was stopped early when analysis of preliminary data showed a slight excess of heart attack deaths in the subjects in the group who were striving to lower their A1cs.
This is all most doctors ever heard about ACCORD--that lowering A1c led to an increased risk of heart attack. What they didn't hear about was the methodology used in the study. That methodology makes it very clear that it wasn't the lowering of blood sugars that caused the deaths, but the way the study attempted to lower A1c.
ACCORD studied only people with long-standing Type 2 diabetes who had been diagnosed with heart disease before the start of the study. These patients were put on a statin drug (which we now know can further raise blood sugar) and a fibrate drug.
Then the researchers set out to lower blood sugar by putting their subjects the discredited high carbohydrate, low fat diet--which a large body of research has shown not only raises blood sugar but worses triglycerides and LDL. To counteract the blood-sugar-raising effect of this diet, the ACCORD researchers put the study subjects trying to lower blood sugar on a cocktail of every diabetes drug available at the time.
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rishad14
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Absolutely correct. Diabetics once struck cannot be cured. That is because the beta cells of pancreas are dying or have died. We can manage the diabetics, with Food, Exercise, and medicines. Metformin plays a wonderful role. If this is not suitable persons can try solw release metformin so that side effects are minimum. Secondly Glucobay also plays a very good role in reducing the role of carbohydrate. This is my personal view only
GLIPTINES ALSO WORK VERY NICELY SPECIALLY WITH METFORMIN,ESPECIALLY IF USED EARLY IN THE COURSE OF DIABETES,AND IT HAS ALSO SHOWN TO DECREASE THE DEGERATION OF BETA CELL AND IN SOME STUDIES MITOSIS OF BETA CELLS AND BETA CELL PRESERVATION,OF COURSE PROBLEM IS THE COST
ACCORD STUDY IS AVAILABLE FOR ALL,AND NO WHERE I HAVE WRITTEN THAT IT IS ORIGINALLY MINE,ITS MUST KNOW WHAT ACCORD SAYS POSTED BY ME,IF YOU DNT LIKE TO READ MY BLOG DNT READ THEM,WHY AT ALL ARE YOU BOTHERED SO MUCH ABOUT WHAT ABCD IS WRITING AT HIS /HER BLOG..THIS IS A PUBLIC PLATFORM TO SHARE WHAT YOU KNOW,WHAT YOU READ,MAY BE YOURS,MAY BE OTHERS
THIS IS AN EXCELLENT DELIBERATION OF YOUR VIEWS AND MY UNDERSTANDING GOES THE SAME,I AM NOT A DIETITIAN BUT I THINK YOU ARE RIGHT. YOU HAVE BRIEFED EVERYTHING IN SHORT. IN KOLKATA MOST PEOPLE USE MUSTARD OIL,THEY DO NOT PREFER COCONUT OIL,ITS NOT IN THEIR FOOD HABIT,AND THEY CONSUME LOT OF STARCH WHAT WE CALL BHAAT
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