Anyone tried coQ 10 supplements?

There was a study 're coQ 10 and PD but the study was discontinued. Anyone heard of it?

[Bitbit]

Yes. No proven benefit for pd. it is proven to be good for the heart. I take 1 tab daily small dose because I perceive a benefit. Maybe it is psychological, but I won't stop it. When my meds got balanced a year ago I was afraid to change a thing. I am not needing sinemet yet, just azilect and the coq10.

[compucure]

Yes but not effective for me I am sorry to say. Tony

[jillannf6]

hi iam on a smalll dose too and i have no treally noticed any difference

but i am still takign it for hte Psp

lol JIll

[anbu]

My family doctor ( not my neurologist ) gave it only last week. Yet to see results.

[hilarypeta]

Yes i have taken them for 7 yrrs al ong with vit c omega 3 s etc..good for heart as well. Not on meds.

[Hidden]

Thanks everyone. Appreciate your inputs

[silvestrov]

I am on coq10 and it has helped me and there are problems with both studies and its perceived benefits. In 2002 a Univ of Calif/San Diego? study noted that patients taking 1200 mg a day had 44 percent less symptoms. In 2011 another study was performed with coq10 at even greater doses 1200 and 2400 mg a day and they could not duplicate the results. Both studies were flawed because they used vitamin E with coq10. To clarify this point, a 2003 hypercholesterolemia study noted that the serum coq10 counts were not as high as they should be and the author attributed it to taking vitamin e with coq10. Here is the abstract for you to read:

archneur.jamanetwork.com/ar...

Basically, I have taken it in doses from 1200 - 2100 mg a day and it has benefited me by helping to suppress the symptoms. It has helped to put a break on the disease and the sooner you take it after the initial diagnoses the better.

Along with coq10 I am taking lots of magnesium, magnesium chloride - transdermal application, along with acetyl l carnitine and lipoic acid. Combined they help to even out brain/body energy production and eliminate many of the symptoms.

Here is the original 2002 coq10 study:

archneur.jamanetwork.com/ar...

The followup in 2011: clinicaltrials.gov/show/NCT...

[Hidden in reply to silvestrov]

thanks for your info. much to read and consider...

[PatV]

I tried at one point. It was too much to take to be MAYBE effective and way too expensive, and the only way you could see whether it worked is during an autopsy. So I have enough pills to take.

[srarndt]

Yes, I was on it for years after the '02 study, and never noticed an iota of difference. I stopped wasting my money on expensive urine after the '11 study was cancelled due to findings that "The investigational drug is unlikely to demonstrate efficacy over placebo for this indication." (However, no safety issues were discovered.)

Bottom line, it can't hurt...give it a whack if you'd like...who cares if it doesn't help the gross majority of folks who try it...if if works for you - that is marvelous!

Steve

Bisbee, AZ

[silvestrov]

Best wishes. I discovered this info because I am making a PD documentary about how I self-treated PD with natural supplements. Many PD patients may have the following deficiencies:

Magnesium, DHA omega 3, vitamin B12 (in the form of methylcobalamin), iodine, vitamin D and, of course dopamine.

[carolineb211]

I have been taking 300mg a day and definitely feel a difference in my energy levels. My other symptoms remain unchanged.

Caroline

[maryalice]

I read the study, but I don't agree with it. I take CoQ10 and it seems to help with lack of energy. Blessings.