RASAGILINE?

[JennyP2025]

Looking for any information. My ND has suggested using it with Mucana.

[michelagvolpe]

since i managed to convince my neurologist to give me rasagiline, the off times have lasted longer. i take it an hour and a half to two hours after sinemet.

[JayPwP in reply to michelagvolpe]

Why are you taking it if your off time has increased?

[michelagvolpe in reply to JayPwP]

i don t want to increase sinemet and rasagiline is better for neurons and less dangerous than sinemet

[JayPwP in reply to michelagvolpe]

But it is not serving the purpose

[michelagvolpe]

rasagiline keeps your dopamine alive for a longer time before it dies

[healthabc]

I'm 10 years in. Taking sinemet & macuna. Is there any benefit to taking rasagiline at this late a time? Would it help my ON time?

[4000Nights]

Short answer: Take it ASAP!

PD Meds are directed at two separate objectives:

- Slowing the progression

- Treating the symptoms (tremors, stiffness)

I went on Azilect (rasagiline) thirteen years ago because it was believed by many to slow progression. A worldwide, multi- institutional clinical trial of rasagiline ’s potential for neuroprotection was published in 2008 and follow-up data from the original studies has also been examined closely. These results suggest that the use of rasagiline earlier in PD may offer the greatest long-term advantage and modify the symptomatology over time. Rasagiline works best if taken early. I highly recommend it. Again, thirteen years and minimal progression.

I take Carbidopa/levodopa for symptoms and although it has had minimal effect on my tremors it has had very positive effects on other symptoms (movement improved and the ‘mask’ is gone).

[JennyP2025 in reply to 4000Nights]

Thank you so much! I was diagnosed six months ago and my progression has been slow.