B6 levels high, can that affect meds and how they work with PD? Any one have experience with this?

[cjCardio53]

B6 high. Is that affecting my FOG symptoms with PD?

[Gcf51]

Look a park_bear 's post. healthunlocked.com/cure-par...

[Gcf51 in reply to Gcf51]

But as compelling as the argument is, I can't take because it reduces the effectiveness of my C/L. I rely on my B complex to provide enough.

[park_bear]

The blood test for B6 tests for the active version of B6. High levels of the active version will do no harm. The inactive version of B6, pyridoxine, is toxic in quantity, but this is not measured by the blood test. Some doctors do not understand this distinction and will be concerned about B6 toxicity as a result of the high levels measured, but this concern is misplaced.

For more detail see: healthunlocked.com/cure-par...

[stlewy in reply to park_bear]

Park_Bear, is there a B-complex brand you recommend that has the non-toxic Bs (active P5P vs. pyridoxine)? I see Amazon sells b6 active p5p, but I was looking more for complex multi-b (b1, b2, b6, b12).

[park_bear in reply to stlewy]

I use Seeking Health B Minus which contains 20 mg of P5P. seekinghealth.com/products/...

It lacks folate and B12. I supplement B12 separately with Seeking Health adenosylcobalamin. seekinghealth.com/products/...

I avoid folate in any form because supplementation is carcinogenic. See my writing here for details: tinyurl.com/ycdrz5lj

[stlewy in reply to park_bear]

Thanks park_bear for the info. I have just ordered the B Minus thru Amazon.

[Eryl]

B6 is a regulator of inflamation and it is also depleted by inflammation. Acute inflammation is good as it soeeds uo healing following trauma but chronic, long term inflammation causes a huge amount of damage especially to the nerves. B6 deficiency has become more common with the proliferation of processed food (which is high in carbohydrate and low in nutrition) and vegan diets as the highest sources of B6 are meat (especially red meat) . pmc.ncbi.nlm.nih.gov/articl...

[park_bear in reply to Eryl]

Vitamin B6 as a cofactor required for over 100 different enzymatic reactions, including the conversion of levodopa to dopamine.