Is there a list of currently active trial... - Cure Parkinson's

Cure Parkinson's

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Is there a list of currently active trials using stem cells?

Squarepusher profile image
16 Replies

wondering if someone can spare me the time required to look them up one by one

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Squarepusher profile image
Squarepusher
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16 Replies
Boscoejean profile image
Boscoejean

clinicaltrials.gov/search?l...

Daisies22 profile image
Daisies22

This is/was the largest database for clinical trials, as far as I know."Parkinson's disease" and "stem cells" returned 10 pages of clinical trials, inclusion & exclusion criteria, main objectives of the trial etc:

clinicaltrials.gov/search?c...

Boscoejean profile image
Boscoejean

Are you interested strictly in stem cell clinical trials in Parkinsons? Are you interested in clinical trials in the US or somewhere else?

Squarepusher profile image
Squarepusher in reply toBoscoejean

PD, US only is ok, but wouldn't mind knowing what's happening worldwide

Boscoejean profile image
Boscoejean in reply toSquarepusher

clinical trials.gov has a new system - Daisies 22 did list all the clinical trials and some have been completed - clinical trials.gov 's old system was so much easier to use I don't know what possessed them to change it So if a person narrows it down to trials that are recruiting or listed but not yet recruiting or enrolling by invitation this list involves those.

clinicaltrials.gov/search?c...

Squarepusher profile image
Squarepusher in reply toBoscoejean

thank you for these generous replies. I guess I was thinking about it like the stock market - sure you can list the 6000 companies that are listed, but which ones matter, what are the top 100 that those in the know have their eyes on. (For cell therapy trials -which ones do those in the know care about - because they have big money/big names behind them - for example, or because they have a great deal of logic to them). Sorry my question was not formulated well in the beginning

Boscoejean profile image
Boscoejean in reply toSquarepusher

Honestly I wish I could find a way of finding these trials other than clinicaltrials.gov : )

Believe me I have tried keying in a lot of questions and most of what comes up seems quite questionable or probably the aim is profitability rather than doing all the work that would be required to set up a clinical trail in the US that the FDA would approve.

Hope Biosciences in Texas has done and is doing clinical trials using stem cells that were in compliance with FDA guidelines.

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A preliminary clinical trial in California

clinicalconnection.com/default

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This article is about planned stem cell clinical trials in New York state

mskcc.org/research-programs...

Investigators from Memorial Sloan Kettering, along with colleagues from Weill Cornell Medical College, have received a contract from New York State Stem Cell Science (NYSTEM) for almost $15 million over five years to develop a stem-cell-based therapy for Parkinson’s disease. NYSTEM works to further the agenda of the Empire State Stem Cell Board, whose mission is to foster a strong stem cell research community in New York State.

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Arizona

parkinsonsnewstoday.com/new...

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Korea but this involves embryonic stem cells

parkinsonsnewstoday.com/new...

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California

parkinsonsnewstoday.com/new...

Squarepusher profile image
Squarepusher in reply toBoscoejean

I hear you. I'm sure the people inside Bayer or Novo have a shortlist of 25 that matter, I just wish someone inside would leak it to this website

Squarepusher profile image
Squarepusher in reply toBoscoejean

I'm betting on South Korea. Those people never quit. It is in their DNA

Boscoejean profile image
Boscoejean in reply toSquarepusher

seems likely

Boscoejean profile image
Boscoejean

I think there are a few spaces left in the Hope Biosciences clinical trial in Sugarland, TX.

The contact information is in the clinical trial listing along with the criteria for being in the trial like age and the fact that the person needs to be 2 years post diagnosis to participate.

clinicaltrials.gov/study/NC...

Squarepusher profile image
Squarepusher in reply toBoscoejean

Thanks. I have people I can stay with in Sugarland so this may work

Squarepusher profile image
Squarepusher in reply toBoscoejean

I looked at it. I'd like to find a single-arm dose escalating study rather than a double-arm placebo control study. Things are getting worse here and I don't want the placebo

Boscoejean profile image
Boscoejean in reply toSquarepusher

yes very hard to find something like that - I did read about some trial in Florida but they make the person pay for it which seems questionable to me - I have been told that the FDA isn't that likely to go with a clinical trial that does not involve placebo and a system that has a lot of measures in place to assess benefit or lack of benefit

Squarepusher profile image
Squarepusher in reply toBoscoejean

Not sure about that. I don't think Biomarin's gene therapy trials for Hem A had a placebo; can't remember; nor did the SGMO/PFE trial.

Boscoejean profile image
Boscoejean in reply toSquarepusher

It does seem like sometimes that is not the case especially in conditions where the symptoms are life threatening

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