If new ribosomes are created by existing ribosomes, how was the first ribosome created?

[jeffreyn]

This "chicken and egg" question occurred to me while reading an interesting article [1] concerning Amyotrophic Lateral Sclerosis (ALS).

I also saw parallels with some aspects of PD research.

"These proteins end up collapsing the cellular clearance systems, which finally leads to the death of the motor neurons."

"We must find ways to reduce the production of ribosomes so that waste decreases, while still keeping a sufficient number to guarantee the correct functioning of the cells." (c.f. the posiphen approach to reducing alpha synuclein)

[1] MedicalXpress article: Accumulation of 'junk proteins' identified as one cause of aging and possible source of ALS.

medicalxpress.com/news/2024...

[peminc]

Pffft. Easy answer!Repeat: "If new ribosomes are created by existing ribosomes, how was the first ribosome created?"

Aliens from outer space! Just watch the movie Prometheus. Next question?