Whole Lemon might help Carbidopa/Levodopa work better plus many other health benefits. pubmed.ncbi.nlm.nih.gov/820... youtu.be/LSwP5eMS1Uo?si=raY...
Can we boost Carbidopa/Levodopa results w... - Cure Parkinson's
Can we boost Carbidopa/Levodopa results with lemons?
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Grapefruit juice has an effect. Apparently lemon does too:
" lemon juice significantly inhibits by 60+/-3% the CYP3A4-mediated oxidation. Grapefruit juice inhibits this activity by 82+/-4%. The mechanism of lemon juice inhibition is competitive, whereas it is mixed for grapefruit juice."
Application to drug-food interactions of living cells as in vitro model expressing cytochrome P450 activity: Enzyme inhibition by lemon juice
July 2001Talanta 54(5):983-7
The problem is that this affects many other drugs too; leading to increasing their potency, possibly to too high a level.
I tried for some time to swallow Levodopa with lemon juice, but I didn't notice an extension of the "On". I also decided to stop because I had to deal with the nausea caused by ingesting the juice on a empty stomach.
I was instructed to take my Levodopa with ascorbic acid vit C
I’m doing this but mixed results