Sinemet not working.

[Gigi_12]

I was diagnosed in 2021 and have been taking this and doing well. I'm up to 1 1/2 tabs(25-100) 5 x a day. In the last few weeks, I get b anxious, lightheaded and weak about 15 minutes after taking my meds. It completely shuts me down . I'm waiting on my neurologist for directions. One was to switch to Rutary. Any other people have its happen?

[park_bear]

see this discussion: healthunlocked.com/cure-par...

[rhyspeace12]

Rytary was a great switch for my husband. there was no more "wearing off."

[kgold in reply to rhyspeace12]

What is his dosage and timing of Rytary? My husband is on it and I'm not sure if he's dosed correctly. Thanks.

[Champman]

I had the same experience so I cut back to one tablet. My blood pressure had dropped of the chart. Met with my doctor who upped the dosage but added MIdodrine (sp?). Now we're back to somewhat normal.

[Gigi_12 in reply to Champman]

Thank you. I'm more worried about the weakness, stomach issues and anxiety. Still waiting to hear from neuro.

[111BANDIT]

perhaps you might consider going to a different movement specalist.

[Gigi_12 in reply to 111BANDIT]

This is my new one.

[rhyspeace12]

My husband died almost 4 years ago at the age of 80. I will go look at his bottle of Rytary and see what dosage he was on.

[rhyspeace12]

He was prescribed Rytary from his motion specialist. His regular neurologist was a horrible man who said he didn't want my husband as a patient and no one else would either. He made me cry with my poor defenseless husbnd lying there as he said it. The idiot was so clueless he didn't even know what "wearing off" was.

[Tayogi]

that’s exactly how I felt when I was overdosing. Maybe try reducing?

[Gigi_12 in reply to Tayogi]

That's what I did. After trying 2 tablets for

[Gigi_12 in reply to Tayogi]

I went back to 1 1/2 tablets but got the same response. Yesterday I tried 1 tablet but think I've really messed myself up even though the nurse okd that. All my symptoms are worse from restless legs to swallowing. Will keep emailing the neuro for help. She's very good so can't imagine not getting an answer.

[JohnPepper]

I'm sorry to say that NO MERDICATION REVERSES PD! I took medication for 2 years and it did nothing. Nobody claims to freverse PD other than FAST WALKKING, which has been proved in clinical trials by the Mayo Clinic in the USA.

[KERRINGTON]

So, how are things, has your neurologist been able to help you yet ?

[Gigi_12 in reply to KERRINGTON]

I finally had a telehealth meeting with her nurse practiconeer. She prescribed Neupro which is a patch you change daily. I have been using it 5 days and it had helped with the restless legs so I sleep better but hasn't done much for my leg weakness. There are multiple strengths and she started me on the lowest one. I take this and the Sinemet.