Gut-first theory of Parkinson's disease gains traction

[Farooqji]

The gut-first theory of Parkinson's, originally proposed 20 years ago, started to intrigue Sulzer after his own research pointed toward the role of an autoimmune response in Parkinson's.

news-medical.net/news/20230...

[pdpatient]

Farooqji,

Nice article. I am coming across a lot of research Information these days about the gut brain connection.

[crewmanwhite]

Dr James Parkinson proposed treatment of gut and bowel in his essay dated 1817. This was completely ignored until just a few years ago to the detriment of those with PD.

[stocktiki in reply to crewmanwhite]

Link to treatment?

[LAJ12345 in reply to crewmanwhite]

This would also be pre junk food and pesticides? so problem in the gut must be due to some natural food allergy? Gluten/dairy? Or due to unbalance diet with insufficient nutrients/fibre? (Too much meat, not enough vege?)

Although heavy metals might have been a factor

“What pesticides were used in the 1800s?

Arsenic, cyanide and other natural poisons have been used for centuries to kill insects and rodents in homes and on farms. In the mid-1800s, farmers found they could use a common, arsenicYcontaining paint pigment, called Paris green, to kill insects in their fields.”

“When did they start spraying pesticides?

Pesticide - Wikipedia

Some sources consider the 1940s and 1950s to have been the start of the "pesticide era." Although the U.S. Environmental Protection Agency was established in 1970 and amendments to the pesticide law in 1972, pesticide use has increased 50-fold since 1950 and 2.3 million tonnes (2.5 million short tons) of industrial…..”

“What did people eat in the early 1800?

Cooking in the 1800s (from Tar Heel Junior Historian) | NCpedia

Most fruits and vegetables were grown on the farmstead, and families processed meats such as poultry, beef, and pork. People had seasonal diets. In the spring and summer months, they ate many more fruits and vegetables than they did in the fall and winter”

[Hidden]

Interested to hear on radio recently that scientists have linked IBS and other gut disorders with later PD diagnoses