Do you keep medications in the container they are received in? Inactive Ingredients may be Active.

The inactive ingredients are different among generic drugs. One of the generic carbidopa-levodopa brands has a filler in it that is very sensitive to moisture and light. The tablets are not enteric coated and the tablets do not have a shine like most tablets. They are manufactured and then shipped in the white aluminum sealed pill bottles. Storing them in pill boxes or the brown plastic pill bottles isn’t recommended. I find the uncoated tablets hard to swallow and it feels like they catch in my throat. It looks like they interact with some mouthwash and toothpaste making a foam. If you notice a difference in your meds, you may want to check the inactive ingredient list.

[park_bear]

Medications can also contain detrimental inactive ingredients, such as titanium dioxide which is banned in Europe due to adverse effects, or talc, which is nothing short of insane in my opinion.

[Hidden in reply to park_bear]

Fillers are especially alarming when you consider their safety is based on short term use and an average number of tablets. Add a slow digestive tract, multiple doses and the fact that some fillers are in food and cosmetics and one becomes a label reader.

[Daisies22 in reply to park_bear]

Thank you for the information. I didn't know that. I just checked my medication (Madopar 100/25) and it indeed contains both talc and TiO2! I live in the UK. medicines.org.uk/emc/produc...

[Hidden in reply to Daisies22]

Thanks for the link. I was wondering how these ingredients are used elsewhere.

[Daisies22 in reply to Hidden]

You are welcome.I was wondering why these ingredients are allowed to be used in medications and food stuff in the first place!

[park_bear in reply to Daisies22]

Additional detail regarding titanium dioxide in my writing here:

Titanium Dioxide In Food – Not A Good Idea

tinyurl.com/yxus4t6f

[Hidden in reply to park_bear]

I found one formula listed to determine doses and maximum daily exposure to drugs uses an average person at 82k or 180 pounds. So a 120 pound person would probably be defined as “drug sensitive “ because they are getting an average dose for a 180 pound person. And it didn’t address how many tablets per day. I wonder what is considered an average number of tablets per day. Another variable to consider.

[Daisies22 in reply to park_bear]

Apologies for taking too much of your time recently. I was wondering if you have encountered (I have not) a scientific paper discussing Rotigotine and difficulties initiating movement when used with L-dopa. This is another thing that's happening to me but I would prefer to have an actual peer-reviewed paper before I try to convince my Neurologist that this symptom exist:

"Movement difficulty: When used in addition to medications containing levodopa, rotigotine increases the risk of experiencing difficulty starting voluntary movement and can increase the side effects of levodopa. If you experience worsening side effects of these medications, talk to your doctor or pharmacist.

Link: medbroadcast.com/drug/getdr...

Thank you in advance!

[Hidden in reply to Daisies22]

Hello. The FDA has a 44 page document online. It is under the name Neupro. This might help. The agency is called the (US) Federal Drug Administration.

[Daisies22 in reply to Hidden]

Thank you!

[park_bear in reply to Daisies22]

Oh Daisy! It is a blessing to be able to be of service, so there is no need to apologize!

I found this which I believe is relevant:

ncbi.nlm.nih.gov/pmc/articl...

[Daisies22 in reply to park_bear]

Thank you so much!