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Excess Iron in Brain Cells Worsens Parkinson’s Symptoms, Mouse Study Shows

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pvw2
9 Replies

Excess Iron in Brain Cells Worsens Parkinson’s Symptoms, Mouse Study Shows

parkinsonsnewstoday.com/202...

"While excess iron in the brain often accompanies Parkinson’s disease, it remains unknown whether the iron overload actually causes the neurodegenerative disorder or is merely a product of it."

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"This new research does not answer the question of whether excess iron in the brain can cause Parkinson’s, the researchers noted. However, it does show how such abnormal iron storage contributes to the disease’s progress, and increases scientists’ knowledge of how iron is regulated within the brain."

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Astra7 profile image
Astra7

I’m so sure my 2 iron transfusions gave me PD. Wish I could get a brain biopsy. No chance if any medico even considering that though😟

parkie13 profile image
parkie13 in reply toAstra7

What do you mean? What did you have?

pvw2 profile image
pvw2 in reply toAstra7

Remember PD shows up after 50 to 70% of the substantia nigra (SN) dopamine neurons are lost, and PD usually progresses after diagnosis at about the same rate as before the diagnosis. Thus, unless you got the iron transfusions 20 years before PD diagnosis, they are unlikely the cause. What is likely is the iron transfusions could have brought out the PD symptoms of PD already in place.

pvw2 profile image
pvw2 in reply toAstra7

In the link on the following page they use imaging to detect iron, but double if insurance would cover it.

healthunlocked.com/parkinso...

Astra7 profile image
Astra7 in reply topvw2

Thanks. That is interesting. I had an mri when first diagnosed. I’ll ask my neurologist if he can see anything to do with iron levels.

He’s pretty old school though 🙁

pvw2 profile image
pvw2 in reply toAstra7

He may have needed to look for iron during the MRI. Note: heavy metal exposure is a known cause of PD, and my major exposure to elemental mercury was 28 years before being diagnosed with PD. We need iron to live. Heavy metals like mercury and lead are only poisonous. Copper (not heavy metal) is a necessary trace element, but too much can cause PD. Usually too much iron will temporarily turn you teeth black on the inside.

Astra7 profile image
Astra7 in reply topvw2

Where did the mercury come from?

pvw2 profile image
pvw2 in reply toAstra7

I worked in a building where they were growing mercury cadmium telluride single crystal and the ampule broke sending mercury vapors throughout the building before it could be evacuated.

rescuema profile image
rescuema

Excess accumulation of any metal/toxin in the brain can be bad for neurological symptoms. The better question is why the toxins are accumulating in the brain with compromised detox pathway if not due to toxic exposures. Deficiencies in molybdenum, iodine, selenium, B's, C, antioxidants, ...etc?

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