levodopa

[whiststev]

Hello,

Does Levodopa help a person who Has symptoms of mild cognative impairment with early onset PD?

TIA

Steve

[MBAnderson]

I don't know if it does or doesn't, but this study says it does.

Here is some hope anyway.

"This finding is consistent with the results of previous studies providing evidence that levodopa has a positive effect on cognitive impairment [12-16]. Levodopa improved the neuropsychiatric scores for verbal attention and memory deterioration in patients with PD who had or did not have dementia [12]."

ncbi.nlm.nih.gov/pmc/articl....

[JohnPepper]

If you are heading towards having Parkinson's Disease, then now is the time to stop the progression of PD by starting to do regular exercise. The Mayo Clinic Study done in 2019 proves that 'High Intensity Aerobic Exercise' produces a substance named GDNF. That substance repairs the damaged brain cells and, you get better! I don't want to knock medication but there is none available that slows down or stops the progression of PD. So why wait until it is too late to get into the good habit of walking. I started fast walking in 1994 and by 1998 most of my movement symptoms had disappeared and have stayed like that until four or five years ago, when I was unable to walk fast, due to other health problems. I am now 88 years old and have started the fast walking again. I still live a normal life. I can send you all the information you need to make this happen to you.

[dentonpark in reply to JohnPepper]

Been following you for years.....and high intensity exercise helps!

[b5p10]

Having been diagnosed wit PD in August 2021, I was prescribed Levadope 50mg per day ,in divided doses, increasing over 6 weeks to 300mg per day. I have increased only to 150mg per day but have added Vitamin B1 and also a red hat coronet. However I do exercises designed for PD on YouTube virtually every day and so far have minimal evident symptoms. The classes cover not only physical movement but also voice and cognitive recognised problems with PD. I feel much better for the exercise although I can only do 30 minutes at a time. My excuse is that I am 80 years old and, although most are done sitting on a chair, it is surprising how energetic they are. I am hopeful that these fun sessions will slow the progression.

[JohnPepper in reply to b5p10]

Hi. All exercise is good for everybody, but some of us exercise too much. The ideal is to only exercise any group of muscles every second day, at the most. The only exercise that has any effect on the progression of PD is 'High Intensity aerobic exercise', which must be maintained at that high intensity for a maximum of one hour every second day.

So, you can exercise your upper body every second day and on the intermediate days you do the Fast Walking, which is the only type of exercise the anybody can maintain at the maximum level for one hour.

Don't think that you have to start the fast walking for one whole hour, immediately! You must start at whatever you can do and every second week, raise it to the next level you are able to do. At the age of 60, I was only able to walk for 15 minutes before I had to slow down. Whenever I reached the point where I could not maintain the top speed I was advised to STOP. It took me 5 months to reach one hour. Never do more than one hour, it is not necessary and does not serve any purpose.

You do whatever you can do at the beginning and stick to that time for two weeks, then on the first day of the next two weeks toy see how long you can walk at top speed and then stick to that time for the next two weeks. When you reach one hour, then continue to walk faster, but NEVER FOR MORE THAN ONE HOUR!

Keep in touch! Good Luck!