Diagnosis of idiopathic PD based on MDS criteria with bradykinesia plus one of the other cardinal signs of PD (resting tremor, rigidity), without any other known or suspected cause of parkinsonism
On symptomatic PD medication, with stable doses for at least 3 months prior to baseline
A diagnosis of PD for at least 3 months to maximum 3 years at screening
MDS-UPDRS Part IV score of 0 at screening and prior to randomization
Hoehn and Yahr (H&Y) Stage I or II in OFF medication state at screening and prior to randomization
Dopamine transporter imaging with single photon emission computed tomography (DaT-SPECT) imaging consistent with dopamine transporter deficit, as assessed by the central reader
No anticipated changes in PD medication from baseline throughout the study duration based on clinical status during screening
Willingness and ability to use a smartphone application to measure PD-related symptoms for the duration of the study
Willingness and ability to wear a smartwatch to measure PD-related motor signs
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