This is worth your time to look at ... Be... - Cure Parkinson's

Cure Parkinson's

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This is worth your time to look at ... Benedlife.com says it has clinical proof their supplement (take with your regular PD meds) WORKS!

PDWarrior1900 profile image
59 Replies

I just checked their website. Those cost is $165 a month for their supplement.

From:

frontiersin.org/articles/10...

"Conclusion: The present study demonstrated that PS128 supplementation for 12 weeks with constant anti-parkinsonian medication improved the UPDRS motor score and quality of life of PD patients."

"We suggest that PS128 could serve as a therapeutic adjuvant for the treatment of PD. In the future, placebo-controlled studies are needed to further support the efficacy of PS128 supplementation."

Clinical Trial Registration: clinicaltrials.gov/, identifier: NCT04389762.

benedlife.com/

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PDWarrior1900
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59 Replies
park_bear profile image
park_bear

It did not do anything for me.

PDWarrior1900 profile image
PDWarrior1900 in reply topark_bear

how long did you take it for? thanks for the feedback

park_bear profile image
park_bear in reply toPDWarrior1900

I took the full course that I was sent. I believe it was several weeks. Also, I do recall at least one comment from someone saying it did help them.

PDWarrior1900 profile image
PDWarrior1900 in reply topark_bear

thanks for the feedback -- read the other post from another member's experience

House2 profile image
House2 in reply toPDWarrior1900

I just ordered it. I’ll let you know if it works

PDWarrior1900 profile image
PDWarrior1900 in reply toHouse2

thanks for the feedback and GOOD LUCK!

EnterTheDragon profile image
EnterTheDragon in reply toPDWarrior1900

I took it for 4 months and it made no difference

JCRO profile image
JCRO in reply topark_bear

I took it for three months in the end. No obvious benefits. Expensive and difficult to shift thru customs too. Removed from my stack for now.

PDWarrior1900 profile image
PDWarrior1900 in reply toJCRO

thank you for your valuable feedback!

JCRO profile image
JCRO in reply toPDWarrior1900

I tried PNX21 for three months as well. Same, nothing.

Jjm0zx profile image
Jjm0zx in reply topark_bear

Same for me, nothing.

PDWarrior1900 profile image
PDWarrior1900 in reply toJjm0zx

thank you for your feedback.... STAY STRONG!

There are hundreds of international clinical trials RIGHT NOW!

I am confident that a 'MIRACLE CURE' is just around the corner!

PDWarrior1900 profile image
PDWarrior1900 in reply toJjm0zx

thank you for the feedback

Astra7 profile image
Astra7

USD $265 to ship one bottle to aus!!Someone’s making money!!

MBAnderson profile image
MBAnderson in reply toAstra7

Any time any one is selling something that expensive - it's a rip.

Millbrook profile image
Millbrook in reply toAstra7

Crazy prices just not sustainable

MBAnderson profile image
MBAnderson

Another -- save your money.

Except the study was conducted by Ying-Chieh Tsai the founder and primary (& probably sole) stock holder of the of the co. that makes the probiotic.

"... benefits ... PD or autism." Take your pick

He makes another single strain probiotic (PS23) he claims

"Boosts mitochondria function to fight adverse effects of aging

Replenishes BDNF (brain-derived neurotrophic factor) for memory and cognition

Helps maintain muscle strength and increases protein uptake

Balances dopamine (motivation) and serotonin (mood)

Reduces cortisol (stress) levels throughout the body

Lowers inflammation, raises antioxidants and strengthens immune function

Improves GI function and healthy gut microbiota"

Pretty impressive for a single strain - you think?

PDWarrior1900 profile image
PDWarrior1900 in reply toMBAnderson

thanks for the great post!

Boscoejean profile image
Boscoejean

my husband has taken this and there has been no obvious benefit unless maybe a person considers that his progression has been fairly slow - his Parkinson's seems to be more on the left side and it causes some weakness in his left leg and arm and he has tremors in the left hand when it is at rest - on the other hand his tremors in the right hand are more like essential tremor in that they do not seem to be very active until he is trying to use the right hand

Boscoejean profile image
Boscoejean

there are some fairly strong claims for bacillus subtilis PXN21 as well and it supposedly inhibits alpha synuclein aggregation and has other benefits but so far we have not seen a lot of benefit thedailyhealthupdate.com/co...

PDWarrior1900 profile image
PDWarrior1900 in reply toBoscoejean

i've also been taking this ... you might want to read about the clinical study with PD the probiotic plantarum...

----------------------------------------

"Methods: This is an open-label, single-arm, baseline-controlled trial. The eligible participants were scheduled to take 60 billion colony-forming units of PS128 once per night for 12 weeks."

"Clinical assessments were conducted using the Unified Parkinson's Disease Rating Scale (UPDRS), modified Hoehn and Yahr scale, and change in patient “ON-OFF” diary recording as primary outcome measures. The non-motor symptoms questionnaire, Beck depression inventory-II, patient assessment of constipation symptom, 39-item Parkinson's Disease Questionnaire (PDQ-39), and Patient Global Impression of Change (PGI-C) were assessed as secondary outcome measures."

"Conclusion: The present study demonstrated that PS128 supplementation for 12 weeks with constant anti-parkinsonian medication improved the UPDRS motor score and quality of life of PD patients. We suggest that PS128 could serve as a therapeutic adjuvant for the treatment of PD. In the future, placebo-controlled studies are needed to further support the efficacy of PS128 supplementation."

ncbi.nlm.nih.gov/pmc/articl....

kevowpd profile image
kevowpd in reply toPDWarrior1900

Open label studies are useless for measuring efficacy. Its cheaper, easier and more likely to provide an encouraging result (hence why they are popular), but its meaningless.

Boscoejean profile image
Boscoejean in reply toPDWarrior1900

I had already read these

PDWarrior1900 profile image
PDWarrior1900

thank you for the feedback and wishing your husband IMPROVEMENT!

Raphaekg profile image
Raphaekg

Watch out for a trial which has no placebo control group. "Placebo" effects are powerful in PD and can produce notable changes in UPDRS scores. This trial had no control group at all and is pretty much uninterpretable. Save your money.

Missy0202 profile image
Missy0202

I have been taking PS128 for a year without any noticeable benefit. I asked them if there would be duties to be paid ontop of the price and they said there would not be. I was charged duties upon receipt and they credited me back the difference. I don't think they have a handle on international shipping

PDWarrior1900 profile image
PDWarrior1900 in reply toMissy0202

thank you very much for your valuable feedback! STAY STRONG! there are 100s of international clinical trials... RIGHT NOW! I'm confident we are much closer to a 'MIRACLE CURE'!

Jana86 profile image
Jana86

Took this for 90 days....no change at all. Contacted the company and their comment was, "Well all PD patients are different."

PDWarrior1900 profile image
PDWarrior1900 in reply toJana86

thank you for your valuable feedback. STAY STRONG! there are 100s of international clinical trials going on RIGHT NOW! I'm confident that we'll soon see a 'MIRACLE CURE'!

gaga1958 profile image
gaga1958

Have you heard of BiotiQuest probiotic? Interested to hear your take.-

Behind story....marthasquest.com/about

-

biotiquest.com/

PDWarrior1900 profile image
PDWarrior1900 in reply togaga1958

no i haven't heard of this but i'll check it out... thanks for the post!

PDWarrior1900 profile image
PDWarrior1900

i just visited their website... there are only '6' different strains in their so-called: "probiotic supplements" ... (2 of the strains are PD-centric -- which is great)... BUT BUT BUT...

their supplements are NOT sold on Amazon...

I ONLY buy supplements from Amazon so I can read the reviews and RETURN supplements if they don't do anything for me...

LeharLover62 profile image
LeharLover62

Hubby’s MDS just started recommending it. He hasn’t started it yet. He had improvement in his regularity with B. Subtilis. So hoping this one helps also.

John_morris71 profile image
John_morris71

Gave it to my mother for almost 6 months. No difference.

PDWarrior1900 profile image
PDWarrior1900 in reply toJohn_morris71

thanks for the feedback. hoping your mom is IMPROVING!

Millbrook profile image
Millbrook

Hi PD,

For some reason I cannot open and read the 28 replies to your post. Can anyone help?

Just some feedback on PS128.

My husband has been on PS 128 since May/June 2021 and I wrote a post on it. It turned his life 180 around. He did not stumble and his driving was normal. Lately our son noticed that his photos looked different. His facial expressions are natural and beautiful as compared to a year ago when he had on occasions that PD mask. I realised that PS 128 had helped him in not just his motor skills.

Recently I read a report dated December 2021 on PS 128 - I can’t seem to locate it- but it listed spatial judgment as one of the benefits. I realised then that it is really true. When you cannot judge a slight incline or bump you will trip or stumble over it. Similarly when driving, when your judgment improves you stop veering into another lane.

My husband still takes his B vitamins but the greatest improvement was with PS 128 and redlight therapy.

He is not on any medication.

His constipation and gut issues were further resolved when we discovered that he is gluten intolerant. Cutting out gluten has been a game changer too as gluten causes inflammation.

Now, to find something that helps with atrial fibrillation.

PDWarrior1900 profile image
PDWarrior1900 in reply toMillbrook

thanks for the good feedback. i have no idea why you can't see the other posts. try a different browser?

kevowpd profile image
kevowpd in reply toMillbrook

Has he been diagnosed, Millbrook?

Millbrook profile image
Millbrook in reply tokevowpd

Hi Kevin, You asked me this before and I replied previously. He has not been diagnosed but my dad had PD and I recognise the symptoms.

My son who commented on the change in facial expression said he sees this in his dental patients and that I could be right about the PD suspicion.

Just very thankful he has actually improved from 2019.

House2 profile image
House2 in reply toMillbrook

Try taurine for a-fib

Little_apple profile image
Little_apple in reply toMillbrook

Does he by chance have a thyroid issue? I think my Moms atrial fibrillation is due to hypothyroidism.

Millbrook profile image
Millbrook in reply toLittle_apple

No h e does not have a thyroid issue

Millbrook profile image
Millbrook

Thank you. How much taurine? I tried 1000 mg before

House2 profile image
House2 in reply toMillbrook

1000 x 3 times per day

Millbrook profile image
Millbrook in reply toHouse2

Thank you. Will try

Millbrook profile image
Millbrook in reply toHouse2

Thank you very much for your tip on taurine. I read up articles on pubmed on taurine as well. It is really helping him. Since he started taking 1000x 3 times a day, the afib has stopped. Thanks so much and God bless

House2 profile image
House2 in reply toMillbrook

I’m so glad it is helping:)

Millbrook profile image
Millbrook

Wow. Just managed to read other comments from email notification. I am just so thankful.

But the new prices are crazy expensive

Back to making yoghurt

Edit: just checked wellbeingsg.com and they are having sale- 6 boxes of ACTIVE at S$189 which works out to S$31.50 a box

PDMAMA profile image
PDMAMA

We tried it for 3 months and have also tried a probiotic from the health food store. Both really seemed to help increase on time.

PDWarrior1900 profile image
PDWarrior1900 in reply toPDMAMA

thank you for the feedback -- STAY STRONG!

Discogs_discogs profile image
Discogs_discogs

Does anyone have any updates on their progress or lack thereof with PS 128? The SOLACE BENED LIFE company has been aggressively marketing their PS 128 product all over the web. It's a Taiwanese company, but they acquired an American distributor and American marketing team less than a year ago, according to the following press release:

prweb.com/releases/2022/6/p...

However, the people whom the company holds out as their "team" of employees are generally just private consultants, such as marketing consultants, product development consultants, science consultants, etc. who own their own businesses. Solace is just one of their clients. You can Google several of the team members and you will see this in their LinkedIn profiles (none of which mention BENED LIFE or SOLACE).

However, the company has been receiving several positive reviews from people with Parkinson's disease here:

m.facebook.com/story.php?st...

A few people in the link above claim to have found the NEURALLI PS128 product by Bened Life to be a miracle cure which stopped their tremor, cured their gait, and much more. Yet, I'm not entirely sold on the positive reviews because they sound scripted. One of the reviewers has provided three separate reviews aggressively in support of this product. Normally, reviewers only provide a single review, not several.

As for the clinical studies, were they not all conducted in Taiwan? If so, that is where the company is located and, therefore, further inquiry should be made regarding the independence of those studies.

Discogs_discogs profile image
Discogs_discogs in reply toDiscogs_discogs

...... And more rave testimonials from the Solace company itself:

m.facebook.com/story.php?st...

Millbrook profile image
Millbrook in reply toDiscogs_discogs

My husband has been on it and red light for 1.5 years. We are very thankful for it and I have written some feedback for those who are interested.

There are also other posts by other members here. You can make an informed decision.

The product is currently on sale at wellbeingsg.com

Discogs_discogs profile image
Discogs_discogs in reply toMillbrook

Here is the product being sold at wellbeingsg.com, the vendor which you recommended, Millbrook:

wellbeingsg.com/product-cat...

Its PS128 ACTIVE and MIND probiotics do not appear to be the same product as the one being sold by SOLACE BENED LIFE with the testimonials above. Also, does that well-being website still ship around the world? Millbrook, you are located in Singapore, and so is well-beingsg.com, so shipping will not be an issue for you. However, will they still ship worldwide and with ice packs when they do so?

Millbrook profile image
Millbrook in reply toDiscogs_discogs

Hi. There was a long discussion about this on the PS128 thread. The product can withstand certain temperatures and others on the forum have ordered it. You can read their feedback.

There were some issues shipping to the US. You can check with the company.

My husband takes the green pack which is the ACTIV

Another member living in Australia mentioned that he ordered from og.com.sg where the shipping was inexpensive.

He had them shipped to him without the boxes so the shipping weight could be opitimised

Redbird12 profile image
Redbird12 in reply toDiscogs_discogs

Thank you for mentioning this about their team. I noticed this too. I have written the company several times and have not received any response.

I am new to this discussion and site. I found you all by googling “Bened Life Neuralli reviews”.

I’m wondering if there are positive responses specifically to Bened Life Neuralli from Parkinson’s patients (or family, etc.) in the US who have participated in the discussions here. It is expensive and with no response from customer service, I’m hesitant. Thanks so much.

JackAubrey profile image
JackAubrey

My wife recently finished her 6th bottle (6th month) of Neuralli.  I was going to come back after three months and post about our experience, but wanted to extend our trial period to provide more thorough feedback.  So now it’s been 6 months and, as promised, I’m back to share our results.

A few details about my wife and I first:

1. My wife was diagnosed with PD 12years ago.  I am her husband and caretaker.

2. Her symptoms from the beginning have been her right side is weaker than her left and she sometimes catches her right foot while walking as a result.  She very occasionally has shaking in her right leg, but typically this only happens when her medication wears off.  She really has no dyskinesia or dystonia to speak of so we’ve been lucky in this regard.  A few years ago she was diagnosed with SIBO and was given two courses of a powerful antibiotic called Xifaxan which got rid of the SIBO, but she still suffered from IBS symptoms like constipation, gas and bloating afterwards.

3. Her main problem now is her response to the levadopa/carbidopa medication.  She has slowly required more pills more often during the day. She was taking about eight 25/100 pills between 7:00AM and 10:00PM and 2 Sinemet CRs at night before bed. A year ago we added amantadine 100mg (1/2 pill, 2x daily)

4. Her symptoms present as fatigue, slowness, stiffness, etc. if her medication dosage is too low and as agitation, overstimulation and unstable walking if it’s too high.  This is referred to typically as LID (Levadopa Induced Dyskinesia), but my wife doesn’t really have much noticeable dyskinesia.

5. Other than levodopa/carbidopa 25/100, amantadine 100mg, and a few basic supplements, my wife doesn’t take anything else for her PD, with one notable exception which I’ll discuss next.

L. plantarum PS128:

“Lactobacillus plantarum PS128 (PS128) is a specific probiotic, known as a psychobiotic, which has been demonstrated to alleviate motor deficits and inhibit neurodegenerative processes in Parkinson's disease (PD)-model mice. We hypothesize that it may also be beneficial to patients with PD based on the possible mechanism via the microbiome-gut-brain axis.”

The Add-On Effect of Lactobacillus plantarum PS128 in Patients With Parkinson's Disease: A Pilot Study

frontiersin.org/articles/10...

L. plantarum PS128 - published peer-reviewed research - Clinical Studies

benedlife.com/pages/publish...

One last thing I want to clear up for folks in the United States before I share our results.  BenedLife has a patent on L. plantarum PS128 in the US under the brand name Neuralli.  If you’re in the US, you can get L. plantarum PS128 from other countries under other brand names, but by the time you add shipping, the cost will far exceed what you will pay for Neuralli in my experience.  Also, L. plantarum PS128 should ship refrigerated.  That’s not going to happen if shipped internationally. I had to do a lot of research to arrive at this conclusion, but feel free to prove me wrong.  So here’s your source for L. plantarum PS128 in the US: benedlife.com.  Sure wish I’d known this before scouring the internet for hours looking for cheaper foreign sources.

Now to the purpose of this post, our experience with Neuralli aka. L. plantarum PS128:

There is no doubt in our minds that Neuralli is helping my wife in multiple ways.  Btw we have been very strict in our testing by not introducing any new variables or changing her existing protocol in any way.  We apply a scientific rigor and skepticism when we try a new drug, protocol, or supplement.  We chart her progress as we go.  We cannot explain the positive results we are seeing other than the introduction of Neuralli.

Clarity of thought and focus

- The first result we observed after about a month was an improvement in clarity of thought.  My wife takes Neuralli at 7:00AM and 7:00PM every day.  We have definitely seen an improvement in clarity of thought in the mornings, specifically verbal communication and cognition.  We talk about important issues in the morning now and she has a complete understanding, focus and easy communication that used to take much later in the day to achieve.

Calmness

Along with clarity of thought she has experienced a sort of calmness we have not seen in years.  A more stable, peaceful demeanor has developed.  Delboy381 said it about his experience and we agree.  She simply feels more “normal”, as unscientific a statement as this may be.  All I can tell you is.  She’s herself again; best way I can describe it.  

IBS Symptoms

The most dramatic effect – and only after month 2 - is that her IBS and constipation symptoms dramatically improved.  She used to take Miralax every night before bed to be able to go to the bathroom the next day.  Now she rarely takes it at all.  Every morning she goes to the bathroom once or twice.  The diarrhea, constipation, gas and bloating have all but disappeared.  None of the dietary changes or drugs she took for SIBO or her IBS previously have worked as well as Neuralli.  And again, we know it’s Neuralli because she hasn’t introduced anything else or made any other changes.

Improvement in overall PD symptoms and medication requirements

There’s has been an overall improvement in her PD symptoms.  I think this comes from the fact that when your gut, and consequently your immune system, starts to heal, you feel better in general.  She now has more energy to exercise due to the healing of her IBS symptoms.  Her motor symptoms – dragging her right foot while walking and occasional stumbling - have improved. This took about 3 months.

The other thing that’s happening is her need for medication has been decreasing.  At first, we didn’t see a pattern in her daily medication requirements, but now we see in the morning, when she used to immediately require Sinemet upon waking at 5:30AM, she can now sleep until about 7:00 without any medication until she takes her first Neuralli with Sinemet at 7:00AM.  This alone is remarkable.

Also, she takes Sinemet about every 2 hours during the day, but now we’ve been able to cut her pills in halves and quarters and give her less medication as a result.  We’ve seen a change of .25 of a pill here, another .50 of a pill there at various times throughout the day, and yet she has the same or more energy. We’re down to about 6 25/100 pills on average a day now. These findings are very promising considering her trajectory was more pills, not less.

Conclusion

This is where we are after Month 6 and counting.  We are so used to disappointment that we hardly ever use the word improvement anymore, but factually documented improvement unaffected by any other variable other than Neuralli is taking place.  I have no idea what you will experience, but if you ask me if Neuralli is worth a try, I would say yes for sure, especially compared to all the other nasty drug alternatives out there.  Hope this review was helpful.  Any questions, please let me know.

PDWarrior1900 profile image
PDWarrior1900 in reply toJackAubrey

thanks for the detailed feedback and we all wish your wife continued improvement!

JackAubrey profile image
JackAubrey in reply toPDWarrior1900

You are welcome! I wish you the best as well. Thank you for posting on this topic.

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