Discovery of levodopa-induced dyskinesia-associated genes using genomic studies in patients and Drosophila behavioral analyses

[Farooqji]

Similar to the therapeutic effect of Ldopa in patients, acute Ldopa treatment restore the motor defect of

Parkinsons flies, while prolonged treatments cause LID-related symptoms, such as increased yawing, freezing & abrupt acceleration of locomotives

[ddmagee1]

What do you mean by abrupt acceleration of locomotives, Farooqji? I don’t understand that phrase.

[Farooqji in reply to ddmagee1]

This is "abrupt acceleration of locomotion" not locomotives. Mistyping

[ddmagee1 in reply to Farooqji]

Thank you for the clarification! That makes a lot of good sense!

[MarionP]

Have any reference (s) you can pass along to help inquiry?