Any advice about weaning off of levodopa ... - Cure Parkinson's

Cure Parkinson's

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Any advice about weaning off of levodopa and starting amantadine.

6 Replies

I have developed dyskinesia and doctors tried reducing levodopa thinking I was getting too much but dyskinesia persisted.

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6 Replies
Kevin51 profile image
Kevin51

I have lower limb dyskinesia from taking levaDopa. I have to stop LevaDopa entirely for it to disappear. So it's atypical :-( though maybe more like di-phasic. I found CR Sinimet made it easier to live with. I take one 25/100 morning/afternoon/bedtime and currently snap them in two and take one hour apart (not recommended!). A DA Agonist might also be an option. I take 100mg Amantadine daily which helps a little. Best Kevin

in reply to Kevin51

Thanks Kevin. So much to learn. I have stopped sinemet completely(as of today) as per doctors instruction. I have no other motor symptoms.

park_bear profile image
park_bear in reply to

I do not know how much you are taking. Please read my comment here and consider tapering instead of quitting cold turkey:

healthunlocked.com/cure-par...

in reply to park_bear

I have been tapering. Went to 1/2 tablet 3x a day. Then 1/2 tab twice a day (under doctors care) stopped entirely about a week later.

johntPM profile image
johntPM

What type of dyskinesia was diagnosed? What were the doses before and after the change? How long after taking a levodopa pill did the dyskinesia start and how long after did it stop? If the dyskinesia starts about a hour after taking the dose, it is likely to be levodopa induced dyskinesia.

You might want to use the following app to help visualize the situation:

parkinsonsmeasurement.org/t...

in reply to johntPM

Chart looks intriguing but too complicated for me to fill out. I am in hospital and will ask the pharmacist here for help. Thanks

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