37 articles on various neuroprotective agents

[Bolt_Upright]

37 articles on various neuroprotective agents:

frontiersin.org/subjects/ne...

[Hidden]

Great link Bolt! I recently wrote about L Serine if you are interested in that one.And Moringa as an alternative to broccoli as an NRF2 activator.

Regarding Metformin, I recommend researching Berberine instead.

Ginko I recommended by Dr. Dale Bredesen. It lowers blood pressure (if I remember correctly) which is why I’m not personally pursuing it.

Another one that is worthy of the list is Bacopa.

Many on there to dig in to! 😊

Off to have my Bolt Licorice.

[Bolt_Upright in reply to Hidden]

I take Berberine. I am starting to think it helps. Thanks chartist !

[Smittybear7]

Thanks for sharing

[Smittybear7]

How do you know how much to use? Where can you purchase them? Is lithium a prescription? Thanks for your help

[CaseyInsights in reply to Smittybear7]

You can start here - 5mg Lithium Orotate

amazon.com/Weyland-Lithium-...

My spouse use 10mg at present.

[Smittybear7 in reply to CaseyInsights]

What does lithium help?

[CaseyInsights in reply to Smittybear7]

My spouse began using - at my suggestion - as a hedge against potential memory issues. The effect (2/3 months later) was a reduction in anxiety.

But it is good for a ton of stuff. This $10 kindle book has all the reasons why it should be in your arsenals of supplements.

amazon.com/dp/B01FT4OGDI/re...

P.S: I had first ordered a 5mg and a 10mg bottle. This is over a year ago. Since then I have used 10mg. The next order is going to be for 20mg. I use it in my night stack.

[CaseyInsights]

...and here is a paper of an unsung vitamin and an largely unrecognized pathway

Riboflavin Has Neuroprotective Potential: Focus on Parkinson’s Disease and Migraine

Unsung Vitamin: B2 (Riboflavin)

Unrecognized Pathway: Tryptophan-Kynurenine Pathway

The authors conclude -

Indeed, riboflavin ameliorates oxidative stress, mitochondrial dysfunction, neuroinflammation, and glutamate excitotoxicity; all of which are involved in the pathogenesis of a wide range of neurological disorders.

In addition, riboflavin is required for pyridoxine (B6) activation. Riboflavin and PLP, the active form of pyridoxine, play essential roles in homocysteine metabolism, and tryptophan-kynurenine pathway.

Indeed, any accumulation of homocysteine or kynurenines due to vitamin insufficiency can lead to significant neurological consequences.

The paper is a bit of a slog to read. But I would suggest that you do explore the diagrams for a quick insight and as a jump off point for further research if so desired.

frontiersin.org/articles/10...

[Smittybear7 in reply to CaseyInsights]

Thanks

[Smittybear7 in reply to CaseyInsights]

How do you determine the amount of riboflavin to take?

[CaseyInsights in reply to Smittybear7]

Riboflavin is usually used as a prophylaxis for migraine.

The dosage suggested is 400mg. And that's where I started. Used 30 tablets with no noticeable effect or side effects. But I am pushing forward.

Currently have 60 Riboflavin tablets ( 400mg) and 60 Riboflavin 5 Phosphate capsules (36.5mg) and I plan to alternate them over a 120 day period.

The Riboflavin 5 Phosphate is the bio-available version of Riboflavin (B2)

Will begin this experiment soon to see if any thing noticeable happens.

P.S: If you take a good B-Complex you will have at least 50 mg of Riboflavin per capsule.

[Fumaniron]

You are a good dude, Bolt_Upright!

[Gcf51]

Great Link... Many things to ponder...