Adjusting Carbidopa levodopa 25 to 100 mg

[Smittybear7]

Over the past several weeks I've noticed jitteriness in the morning and some involuntary movements of my body. I was currently taking 1 + 1/2 Carbidopa levodopa in the morning. 1 Carbidopa levodopa in the afternoon in one pill in the evening. I began to notice these symptoms since the extra half of Carbidopa was added in the morning. I spoke with my neurologist in a video conference and we decided maybe it was too high a dose. I tried B1 500 mg twice a day and started to have jittery response. I wasn't sure if it was the carbidopa-levodopa for the B1. So I cut the B1 the jitteriness continued. The decision is to cut the extra have to pill in the morning. How long should it take to notice a difference? At what point should I reintroduce B1? My nutritionist muscle tested me 4 b 1 and determined but I should use 500 mg twice a day. I'm wondering when I can restart the B1 to make a determination what's helping. Thanks for your advice

[park_bear]

In my limited experience the reduction in dyskinesia should be immediate.

Also of interest - the difference between immediate release and controlled release:

healthunlocked.com/cure-par...

I would wait for the jitteriness to subside before reintroducing the vitamin B1. Also you might want to start first with just once a day.

[Smittybear7 in reply to park_bear]

Thanks

[enjoy2013 in reply to park_bear]

Just take in consideration if it doesn’t disappear after you return to your previous L-dopa dose that it can be restless legs. What time do you experience the jitteriness?

[Smittybear7 in reply to enjoy2013]

Mostly in the morning

[janers]

I find in the morning I need less of a dose because dopamine has built up in the system overnight, and the stomach is empty. Definitely reduce the morning dose and you should feel the difference right away.

[Smittybear7 in reply to janers]

Thanks Do you adjust your dosage frequently?

[Smittybear7 in reply to janers]

I also noticed the involuntary movements after I walked 1/4 mile today. Could that be from too much dopamine from exercise?

[janers in reply to Smittybear7]

Yes, I have found that after exercise I don’t need a usual dose of dopamine.

[janers]

Yes, I “nibble” on a C/L pill throughout the day as needed. Sometimes I take a quarter or a third depending on how I feel. Usually no more than a half because more than that gives me the jitters.