Levodopa/Carbidopa and vitamin C

[Missy0202]

I am sorry if this was previously discussed but I couldn't find it anywhere. I was told to take my L/C with Emerg-C but I just can't get it down. Can I take it with an Ascorbic Acid supplement instead?

[park_bear]

Sure. The only difference is emergen-C has some flavorings and some traces of B vitamins. I was not aware of the need to take carbidopa levodopa with vitamin C, although it is as it happens I often do..

[Missy0202 in reply to park_bear]

Thanks for the reply! That was one of the first things I was told when I started L/C

[enjoy2013 in reply to Missy0202]

I have seen in the past discussions around the method described here, as a rescue for a better, more smooth absorption of ldopa

López Lozano JJ, PMID: 7786540.

I can't remember where. At the time I didn't try, somehow it looked to me complicated and deemed to fail because of the need to have the solution homogeneous as you sample your next dose. I may have been lazy

[Missy0202 in reply to enjoy2013]

I looked that up, and it was way too confusing to me too!!!

[Sydney75]

This info regarding vitamin C was presented in one of Laurie M. Parkinson's School discussions to improve the bioavailability of C/L in stomach acid. She has spoken of the benefit of citicoline extending life of C/L. I would use plain ascorbic acid as the Emergen C has a bit of B6 in the ingredients which is not to be taken with C/L.

[Missy0202 in reply to Sydney75]

Thank you. I tried that powdered c and couldn’t get it down. That’s why I was asking about a c supplement.

[lenamm in reply to Missy0202]

I use gummys for when I can't do powder - when I'm out. There are 250mg in each gummy of C. Super easy to take.

[Missy0202 in reply to lenamm]

is it Ascorbic Acid ??

[lenamm in reply to Missy0202]

Yes

[Missy0202 in reply to lenamm]

Oh wow. Could you send me the product name? Sounds yummy

[lenamm in reply to Missy0202]

Nature's bounty c gummies

[Missy0202 in reply to lenamm]

Ordered big thanks!

[Marimar70 in reply to Sydney75]

From My knowledge the carbidopa will not be an issue with B6.

[Ob6842 in reply to Sydney75]

Dr. Mischley also has recommended fresh lemon juice of one lemon. Costco, in the US, has a large bottle of organic lemon juice, which is very convenient!

[silvestrov]

According to the following article adding 200 mg of vitamin C to each dose of levodopa will aid in Sinemet/Madopar absorption. pubmed.ncbi.nlm.nih.gov/156...

[Missy0202 in reply to silvestrov]

I had not read that before. Thanks for sending it!

[simonasays in reply to silvestrov]

Question - If you take LD/CD 4 times a day it reaches 800 mg. i am thinking this would be too much.

[Ep0522]

I was told by my neurologist to take with a Little orange juice!

[Jennyjenny2 in reply to Ep0522]

Hi, do you still take the orange juice with the levodopa and do you find it still helps?

[Ep0522 in reply to Jennyjenny2]

I do not, can’t see were it really helps.

[Jennyjenny2 in reply to Ep0522]

Thanks for your reply. 😊

[Divii in reply to Jennyjenny2]

Me neither

[Wind_in_the_trees in reply to Ep0522]

Orange juice will spike your insulin and is a terrible idea. I would not trust any info from a neuro that suggests someone with a brain disease touch orange juice. Insulin resistance in the brain is associated with ALZ and PD.

[Divii]

I take with lemon juice freshly squeezed

[Ob6842 in reply to Divii]

Cosco sells a large glass bottle of Organic lemon juice that’s super convenient!

[Missy0202 in reply to Ob6842]

Thank you. I have not seen that in Canada yet