upadacitinib

[Zardoz]

I don't know if there's a consensus about the skin condition that so many of us PWP's suffer from, whether it's seborrheic dermatitis or atopic dermatitis or exzema but for what it's worth the drug upadacitinib, already approved for use against rheumatoid arthritis shows promise against certain of these conditions.

medicalxpress.com/news/2021...

medicalxpress.com/news/2021...

[freefallmode]

Do PWPs suffer from skin conditions more than the population average? I've asked two neurologists about this and they didn't think so. I'd like to know is there is a research based consensus about it. Anybody know?

[134A in reply to freefallmode]

A couple of years ago I was suffering with bad exema on my hands. I tried multiple creams and lotions to no avail. Then I remembered some food sensitivity testing that I’d had done previously . There was a list of foods that I should eliminate or avoid. Chiefly dairy and wheat. Once I began following the diet, the exema went away and hasn’t come back. If I occasionally “cheat “ and maybe eat a bit of yummy cheese or baked goods, I might feel a bit of an itch on a finger or two which prints me to behave again. I suggest that anyone who is bothered by skin conditions might want to have some sensitivity testing done.

[freefallmode in reply to 134A]

Really interesting. I've had the same experience. Except the itchiness and eczema spread just about all over my body. It's under control as long as I avoid gluten, dairy, soy, eggs and some nuts.Often when I have a food related skin reaction, my PD symptoms get worse, as does medication efficacy.

That's why I'm wondering if PD/skin issues/food sensitivities are related in some cases.

[134A in reply to freefallmode]

It all starts in the gut. We are what we eat.