Withania somnifera shows ability to count... - Cure Parkinson's

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Withania somnifera shows ability to counter Parkinson's Disease

JayPwP profile image

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Withania somnifera (Ashwagandha) is a very revered herb of the Indian Ayurvedic system of medicine. It is useful for treating various kinds of disease processes and especially used as a nervine tonic. Withania somnifera (Ws) contain a wide array of active components including withaferin A, withanone and other flavonoids exhibiting strong anti-oxidant properties. Many scientific studies on Ws were carried out previously that showed its anti-oxidative effect, synergistic effect with other medicinal herbs and its efficiency to increase catecholamines level and regulation of apoptotic processes. Furthermore, treatment of Parkinsonian mice models with Ws has shown neuroprotection of dopaminergic neurons in substantia nigra pars compacta region of mid-brain. The present review enlightens the crucial role of Indian Ginseng to curb neurodegenerative disorder such as Parkinson's disease. Extensive studies are needed to prove its therapeutic efficacy in neuronal disorders.

12 Replies

I take it. Good for stress

park_bear profile image
park_bear in reply to Farooqji

Any effect on your Parkinson's symptoms?

Farooqji profile image
Farooqji in reply to park_bear

There are studies that show that Ashwagandha strengthens the muscles and enhances the exercise endurance. That's why it is often used by athletes

MarionP profile image
MarionP in reply to Farooqji

What does that mean?

Farooqji profile image
Farooqji in reply to MarionP

A study has reported the efficacy of Ashwagandha root extract in improving muscle strength by exercise based evaluation of muscle strength. The study proposed that extract supplementation reduces exercise-induced muscle injury by downregulating serum creatine kinase levels (Wankhede et al. 2015).

Please read this book "Science of Ashwagandha"

filebin.net/d07eyjmijj92qvq0

This is a review article summarizing prior work. It appears that the most advanced prior work was based on the usual rodent model of whether the subject compound protected against toxic compounds causing parkinsonism. This sort of model is not very good because it bears little resemblance to mitigation of actual Parkinson's.

silvestrov profile image
silvestrov in reply to park_bear

Toxin models were the first models of PD and it is good to have them, but, like PB says, they are not models of idiopathic Parkinson's disease. Regardless of this fact, Mucuna pruriens, which many people use has.............. Synergistic effect of Mucuna pruriens and Withania somnifera in a paraquat induced Parkinsonian mouse model

scirp.org/journal/PaperInfo...

Where did chemical model's of PD come from? openvault.wgbh.org/catalog/...

I also found this study:

researchgate.net/publicatio...

Apparently a lot of sources are contaminated by heavy metals so be sure to source it from a reliable supplier

I trust anciest indian medicine (ayurveda) sometime more than our modern medicine. Ashwaganda, turmeric, ghee, mucuna, etc don't need to be supported by modern studies. IMMO

JayPwP profile image
JayPwP in reply to Somic67

Agreed 100%

Hi is possible that you can get low serotonin levels in parkinson also ?

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