Thiamine hcl could be a perfect treatment if it could quell tremors.
It does not. For me it doesn’t. I have fair results with levodopa. I read posts of PWP having good results when they added mucuna to their B1 regimen. I have tried mucuna in the past. Today I am giving mucuna a test.
Teaspoon dose.
8 am / 1 tsp
12 pm / 2 tsp
4 pm / 3 tsp
8 pm / 4 tsp
Update:
Forgot to take dose at 4 pm. That being said, no tremor all night until 4 am. Slept the whole time. Previously I would have night tremors.
So, you’re gonna need a few supplies: a scale, a teaspoon measure, and a calculator. Get a hold of a jeweler scale and get the weight of one measured teaspoon of your powder. It’s gonna be around 3500mg, 3.5g, but we want to be exact. Let’s say 1 tsp weighs 3.5g. Whole bean and pod Mucuna will be around 6% L-Dopa. Extracts can be anywhere from 10% to much higher. But let’s say your brown powder is ground up whole bean and pod @ 6% potency. 6% x 3.5g = 210mg. So one tsp of your powder is 210mg L-Dopa equivalent. I have been schooled to keep my L-Dopa intake at around 1g per day. So your daily dose would be 1 tsp 5x per day. If you want to dose every 6 hours like I do then you could make the dose 1.25tsp. Anyhow you can experiment with it. First find out more about your powder, if it is whole bean or an extract. The manufacturer should be able to give you the L-Dopa percentage. Then weigh it out and do the math. Let me know how it works out. Best of luck - JG
I have read that to compare 1 tablet of sinemet (carbidopa / l-dopa) to mucuna you have to multiply the quantity of mucuna by 5. The exact dose would be 500 mg of mucuna L-DOPA, therefore the amount of mucuna to be taken per dose is 1000mg = 1gr.
I've been taking Mucuna for several years and I've totally stopped my left hand tremors.
It is the Ayurvedic properties of Mucuna that give this result, not the L-dopa of Mucuna.
Concentrates products such as Solaray provide L-dopa but little or no Ayurveda properties after rinsing with hetanol.
You do not need more L-dopa while you are taking Sinemet.
For Ayurveda, take natural (or almost natural) Mucuna such as Zandopa, Banyan Botanicals, Bulk Supplements, Detoxingtrading, indigo-herbs
Their L-dopa content is very low (5 or 6%).
Continue to take your Simenet but at the same time take natural Mucuna powder dissolved in a little water, e.g. to start, one dose of Zandopa (7.5 grams) per day. Slowly increase the Ayurveda dose each day and lower your Sinemet slightly (less than the amount provided by Zandopa).
The maximum limit of Zandopa (2 or 3 doses per day?) will be reached when your stomach starts to protest!
I hope it will work for you.
Update dose experience
I am finding it takes 30 minutes to take effect. Stopping tremors at a single dose of two teaspoons. I won’t take this high dose regularly. I will continue to look for a safe method to reduce the tremors
Supplement-wise, 5g of Mucuna Prurientsdried powder has been used with efficacy in some human studies on Parkinson's Disease and Fertility. This dose or doses upwards of it should be a good starting point.
If your supplement is standardized for L-DOPA and you are supplementing for an effect attributed to L-DOPA, then start with about 1/2 the L-DOPA equivalent and work up if needed (this is due to the same amount of L-DOPA in Mucuna being more bioactive relative to isolated L-DOPA without carbidopa).
If you would imagine ground up kidney beans, it tastes like that. Am talking half a teaspoon each night, to help me sleep. That, combined with 10mg melatonin works for now. Don't have tremor yet though
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