PD: Colonic dysmotility, Enteric α-Synucl... - Cure Parkinson's

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PD: Colonic dysmotility, Enteric α-Synuclein, FMT, Microbiota Dysfunction - a delightful miscellany

5 years ago•7 Replies

PD: Colonic dysmotility, Enteric α-Synuclein, FMT, Microbiota Dysfunction - delightful miscellany.

Accumulation of Alpha-synuclein Causes Colonic Dysmotility Independently of Enteric Nervous Damage in the Early Stage of Parkinson's Disease.

2013.

ncbi.nlm.nih.gov/pubmed/236...

ncbi.nlm.nih.gov/pmc/articl...

Alpha-Synuclein Pathology and the Role of the Microbiota in Parkinson’s Disease.

2019.

ncbi.nlm.nih.gov/pubmed/236...

ncbi.nlm.nih.gov/pmc/articl...

Relation of Enteric α-Synuclein to Gastrointestinal Dysfunction in Patients With Parkinson’s Disease and in Neurologically Intact Subjects.

Hyo Jeong Lee, et al.

Journal of Neurogastroenterology and Motility 2018; 24(3): 469-478

ncbi.nlm.nih.gov/pmc/articl...

Gut Microbiota Dysfunction as Reliable Non-invasive Early Diagnostic Biomarkers in the Pathophysiology of Parkinson’s Disease: A Critical Review.

2018.

ncbi.nlm.nih.gov/pubmed/292...

Parkinson's Disease: The Emerging Role of Gut Dysbiosis, Antibiotics, Probiotics, and Fecal Microbiota Transplantation.

2019.

ncbi.nlm.nih.gov/pubmed/313...

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aspergerian

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7 Replies

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Oceanflow5 years ago

Thanks again for this interesting post! I wonder who out there is willing to give us specialized faecal transplants? Will our Medicare plans pay for it?

Blackfeather5 years ago

Great post! It's very frustrating that FMT could be of great benefit to our gut health and PD, but in USA, the FDA has restricted its availability.

aspergerian in reply to Blackfeather5 years ago

Problem with FMT: if might soon have high efficacy and would turn attention away from habituatedly ingrained PD pharmaceuticals with low efficacy but high gross sales.