Could this newly discovered protein help treat Parkinson's?

[FMundo]

in Medical News Today (ourcced from Journal of Molecular Biology)

medicalnewstoday.com/articl...

[WinnieThePoo]

Interesting one to toss into the current debate about whether A-syn has a real role in PD pathology (and therefore whether regulating it can help the disease) or whether it is a distraction of no relevance, as a couple of recent research papers have postulated.

Personally, I am inclined to the A-syn as villain camp (number of recent interesting papers) and hope HYPE will be a valuable resource

In spite of its slightly unfortunate acronym...

[FMundo in reply to WinnieThePoo]

Yes. HYPE is an unfortunate a choice. Brings back to memory "Differentiating HOPE from HYPE" warhoop of Todd Sherer, CEO of MJFF which he proclaimed on the launch of a second trial of Nilotinib using the design of Georgetown University (whom he cut out of participation). Fortunately GU ran their own trial and it looks like they will report results first.

[park_bear in reply to FMundo]

Like MJFF I have my doubts about the Georgetown U. results. MJFF is in a tough spot because they cannot go public about their issues with GU. Suffice it say I found it odd for GU to report no adverse events for a medication that causes a serious skin reaction in 40% of patients.

[JANVAN in reply to park_bear]

Hi Park_bear : a bit out of the topic >>> but is Sinemet still available in the USA ??

[park_bear in reply to JANVAN]

It is available as a generic, for example see goodrx.com/sinemet-cr

As to the brand name version not sure.