holisticprimarycare.net/top...
"Sulfate deficiency is the most common nutritional deficiency you've never heard of," says MIT Senior Research Scientist Stephanie Seneff, PhD, at the recent Clinical and Scientific Insights (CASI) conference in San Francisco.Seneff
Seneff believes that sulfate deficiency is a major culprit behind most modern chronic diseases and health conditions. But it is one that is largely overlooked......
One reason that I eat cruciferous veggies daily.
Easy way to add sulfur do your daily supplementation routine. Interesting article, also talks about DMSO and its uses.
health-science-spirit.com/m...
I read the information you linked on DMSO and MSM. Thanks for bringing this up. I am going to try one. Have you knowledge of or experience with,,?
I have used both DMSO and MSM. Some people develop a rash from MSM. I experimented at fairly high dose MSM @ 15~20 grams/ day using bulk powder. It is quite bitter, but not in the same way as thiamine powder which seems a bit more bitter to me. I was not a responder to MSM and gave it 5 pounds worth for my oral MSM experiment, but some people get very good benefit from it. I also used it in topical formulations that I made for friends and family who were responsive to its pain relieving effects.
DMSO I have only tried topically and again, I am not responsive to DMSO in terms of pain relief. It had no pain relieving effect for me, but it does for the majority of users. One downside to DMSO, because it disrupts the skin barrier function as part of its process to carry other molecules transdermally into the system is that cleanliness before and after application is important because anything that is on the hands and skin can be delivered into the system if the molecule is small enough, so you don't want to be introducing "bad players" directly into your system. From the shoulders up, DMSO may be too strong for some people because in that area it can cause an uncomfortable to burning feeling on the skin. In fact it can do that almost any where on the body to a person who is sensitive to DMSO. Dmso is a solvent and should be handled carefully for topical application, especially if you are using a purer product such as 99.9% DMSO. It is also available in lower concentrations such as a 70% gel.
Many people get tremendous pain relief from DMSO, I just don't happen to be one of them. DMSO is also used internally for different things such as cancer, but I have never used DMSO for such purposes. Not everybody responds the same way to DMSO or MSM. Applying DMSO to the skin in some people can cause a garlic taste in the mouth or a garlic like sent to emanate from the skin. I have never experienced that effect myself , but it is often reported as a thing.
Art
Myself, I have never used DMSO. About 15-20 years ago I used MSM for quite a while. I've been plagued by stuffed up nose and that relieved it almost right away. Can't remember who I stopped. But just recently I started again, I use a smaller amount, it's an old-fashioned Ice-T teaspoon just a small teaspoon of MSM mixed with water and I drink it. To me the bitterness is not overwhelming. Again, I don't have a stuffed up nose anymore. I buy it at health food store bulk, not very expensive.
I was thinking, maybe that's why we are all so deficient in vitamin D because we don't have enough of sulfur.
westonaprice.org/health-top...
“Dröge11 further discusses how a reduction in the synthesis of sulfate from cysteine in the liver leads to increased compensatory activity in another biological pathway in the liver, one that converts glutamate to arginine and urea. Glutamate is highly significant because it is produced mainly by the breakdown of amino acids (proteins in the muscles), for example, by muscle wasting. The muscle cells are triggered to cannibalize themselves in order to provide adequate glutamate to the liver, mainly, in my view, in order to generate enough arginine to replace the role of sulfate in muscle glucose metabolism. (These activities in the liver and muscles are circular and mutually supportive.)”
I wonder if that’s why very rapid weight loss in PD is associated with a poor outcome.
Interesting
A few questions about how the B1 Therapy is currently administered, and an idea on how to improve results.
PD and iodine deficiency?
Vitamin D supplementation worsens Alzheimer's progression: Animal model and human cohort studies 2022
Fat-soluble B1, for a 25x enhancement at the brain ? 
Vitamin D
