"Methylation cycle", the missing link between stress and PD ?

[Xenos]

If you have not already - it's from past May - do not ask questions, just go and read.

blog.parkinsonsrecovery.com...

[bassofspades]

I give this post a BIG THUMBS UP!!

👍

[Kia17]

👍

[jimcaster]

👍(This seems to be the way the cool kids are responding). 😊. In all seriousness, though, this is an interesting take on B1. I question the conclusion that eventually we can quit taking HDT, but who knows? I do agree that the breakdown in the methylation cycle may be due to unrelenting stress. I was unnecessarily, but really stressed out my whole adult life. Ironically, if not for PD, I'd have virtually no stress now...

[ElliotGreen]

I'm on the fence here.

If we go back 8 months, when this article came out, we get this HU post.

healthunlocked.com/parkinso....

Bailey_Texas asked

"What is the methylation cycle and how does Thiamine affect it? I can find no mainstream medical papers that even use it."

In response, we find the much-lauded Sunvox saying this:

"The term 'methylation' has been subverted by internet quacks and is now being used out of context to describe theoretical improvements in body chemistry. It is the same type of nonsense that you find on the internet about changing the alkalinity of your body."

"Methylation" is really vague. Methylation of what? Methylation by what? What methylation cycle are you even talking about?

sci-hub.tw/https://pubs.acs...

If "methylation" is so centrally important when it comes to thiamine, why isn't it mentioned even once in thiamine's wikipedia page?

en.wikipedia.org/wiki/Thiamine

Give me something more substantive and less handwavey than "the methylation cycle". Tell me, for example, more specifically all the B vitamins do.

[ElliotGreen in reply to ElliotGreen]

This article is more factual.

B-Vitamins, Mood, and Methylation — It’s Complicated

jdmoyer.com/2011/09/03/b-vi...

[fossygma]

The one thing I can't figure out. Are we (with PD) under methylated or over methylated?