SAMe, Parkinson’s disease and Levodopa

[Kia17]

Evidence suggests that levodopa (the drug used to treat Parkinson's disease ) can reduce brain levels of SAMe. This depletion may contribute to the side effects of levodopa treatment, as well as the depression sometimes seen with Parkinson's disease. One study found that SAMe taken orally improved depression without changing the effectiveness of levodopa. However, it is also possible that over time taking extra SAMe could interfere with levodopa's effectiveness.

swedishhospital.com/hl/?/21...

All you need to know about SAMe(S-Adenosyl Methionine)

examine.com/supplements/s-a...

[munchybunch]

I love reading yr posts Kia!

[Kia17 in reply to munchybunch]

Thanks munchybunch

Kia

[Juliegrace]

I considered taking SAMe, but besides the levodopa warning I think I remember that it can effect sleep negatively, something about vivid dreams? It's a while ago, so I may be wrong.

[LauraYu in reply to Juliegrace]

Hi, I have just ordered SAMe. Before I take it, can I consult you? How was your experience with SAMe? Many thanks, Laura

[Juliegrace in reply to LauraYu]

I never took it for the reasons I mentioned above.

[LauraYu]

Thank you for your reply! I saw mixed opinions online, and I am hesitant to take it.