Metabolic, Epigenetic, and Transgenerational Effects of Gut Bacterial
Choline Consumption
cell.com/cell-host-microbe/...
Highlights
•Gut bacteria compete with the host for choline, decreasing
bioavailability.
•Microbial choline degradation depletes methyl-donor metabolites.
•Microbial choline utilization alters in utero epigenetic
programming of the brain.
•Mice with choline-consuming gut microbiota display altered behavior.