I would like to add vitamin B to my regimen.
I read that one have to take them in association (no larges doses of Vitamin B1 without B6 for example).
Am I wrong ? Does anyone have a clue about the ideal Vitamin B complex (including intramuscular shots if necessary) ? Any advisable brand ?
see my recent Posts and Replies
I did, RoyProp. Actually, it's because of your threads about B1 that I've been drawn to taking vitamin B. In fact I am still reading your posts and those of Silvestrov (among others).
And this :
easyhealthoptions.com/brain...
I'm a looking for a "bottom line" type of recommendation.
I take B Complex Plus by Pure Encapsulations which is my favorite brand.
Everybody is different. I take one Cenovis Mega-B tablet every night, this is an Australian brand which I find is very good, for me at least. The ingredients follow:
Vitamin B1 (Thiamine Nitrate) 50mg Vitamin B2 (Riboflavine) 25mg Vitamin B3 (Nicotinamide) 50mg Vitamin B5 (Calcium Pantothenate) 50mg Vitamin B6 (Pyridoxine Hydrochloride) 50mg Vitamin B12 (Cyanocobalamin) 50mcg Vitamin C (Ascorbic Acid) 100mg Biotin 50mcg Folic Acid 200mcg Inositol 50mcg Choline Bitartrate 50mcg
There would be a similar product available in most countries.
You are right - everybody has different biochemistry. I have MTHFR mutation that prevents processing/breaking down folic acid into a bioavailable form and therefore unprocessed folic acid might block folate receptors preventing absorption of natural folate from foods. So my only choice is methylfolate or calcium folinate for folate supplementation. MTHFR polymorphism is very common and because it slows down body detoxification I suspect that it is more prevalent in people with PD. It would be helpful to check blood homocysteine which is usually elevated (over 10) in case of MTHFR/methylation issues and is indirect indicator of MTHFR polymorphism (unless you take levodopa which also raises homocysteine).
Also, in my case B12 is better as methylcobalamin or a combination of methyl-, hydroxy- and adenosyl- cobalamin which have better bioavailability than cyanocobalamin. There is a lot of information on the internet on this subject. Dr. Ben Lynch is my methylation "guru" 
Also, forgot to mention that Silvestrov has good information on the subject:
i'm a firm believer in B-12 injections for better balance, longer energy reserves being maintained, and overall help with stress. Using B12 for about 30 years and you cannot overdose on B 12... more info is available on line google search on B 12.
how often to you take the B12 injection?
I take B 12 once per month and take 1 1/2 cc each time. Be sure to use a 1" needle as B 12 needs to get into muscle ... I use the top of my thigh to make sure I get into muscle tissue. Most of the time it does not hurt.
I too have taken B12, but not directly for PD, albeit for the depression that comes when I was first diagnosed with PD - many of you know what I'm talking about. Depression, along with paranoia and dementia, can be caused by a deficiency of B12. These can have an effect on the brain and nervous system, which sometimes can be irreversible.
I discussed vitamins with my Neurologist a few appointments ago, and he said: "no vitamin or supplement will aid in the slowing down, stopping or, reversing of PD."
That said, I still take a multi-vitamin, a B12, and a D3 every day.
The only thing that I have discovered what does help is vigorous exercise.
I'm taking a B-Complex every day, it's gives my the munchies, which I don't need, now batteling with a weight problem!
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