I’ve been on methotrexate for over a year, and Humira for about 5 months. I’m also on an antidepressant. I have just started to feel the worst nausea and stomach discomfort and it seems like after I take my dose of MTX. I was on 10 tablets weekly and was just switched to 5 after complaining of the nausea. I’m also on Zofran, with little to no luck. I drink mineral water, peppermint tea, sniff and dab peppermint oil, wear Seabands, chew mints. I’m trying it all. The pain is too much, I’ve also started experiencing bouts of diarrhea days after the dose. I’m extremely weak lately and so fatigued.I literally gag whenever I take my pills. And throw up slightly. I have a doctor appt coming up and will be discussing everything. I’m afraid to approach my doctor about the medical marijuana card but at this point I’ll try anything. Has anyone had any luck talking to their doctor and any luck with thc?