Ive been on methotrexatefor about 6 months now. At fitst i didnt have any side effects other than fatigue but abouy a month ago i started noy being able to stomach it. The doc told me to split the dose 3 pills after lunch 3 pills after dinner. But that didn't work either.
I decided to try splitting it farther apart over 24 period. Do you think im messing with my health and this is dangerous or its fine as long as i just take the prescribed dose 1once a week ?
BTW when i split it by 24h i haf no side effects at all.
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Ifayed81
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I take 15mg - 6 pills of 2.5mg - and I split over 24 hours. My Dr said it is perfectly fine as long as you take it within 24 hrrs. I take 3 at dinner Monday and then again at dinner Tuesday. Always with food & lots of water. No stomach problems. Have been on MTHX for about 8-9 months. If you can keep up exercise it really helps.Good luck!
I also took it split through out a 12 hr period but only got up to 15 mg day. Doc said that was fine. Awhile back I read a study that it works fine doing it that way
Of course, talk with your RA doc. My experience with splitting methotrexate doses has been good. I am on Omiprazole for stomach troubles as a side effect. I take this in the morning. After breakfast I take 3 tabs and after lunch I take 4. My doc said I can take with a meal or for better absorption on an empty stomach. I have been on this schedule for many years without problems. Again, talk to your doc about over what period of time you can split the doses. Good luck.
I've been on methotrexate for 12 weeks 20 mg weekly and in the last 3 weeks I'm suffering with blisters in my mouth and so tired can't see specialist until 27/06 was going to ask for injection form
It is good to hear some positive posts on mtxe. I am only in my 2nd week of the lowest dose, 2.5 mg 3 x one day a week. I have now taken the 2nd week several days ago & am happy to say no nausea or other complaints. I was worried about it so this was a relief. But I can’t help but wonder when my rheumy increases the dosage (in Feb) if I can handle it. I have always had a queasy stomach, even riding in the back seat of a car, etc. I have made sure I ate a meal before taking it & am also taking the folic acid every day. Yes, my rheumy said daily. I even called the pharmacist because I continually read where ppl were saying skip the day you take the mtxe. If I reach a point where it makes me sick I will ask about injecting instead.
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