Azathioprine and nausea

[Bigchiefld]

Hi everyone. I started on azathioprine 50mg 2 weeks ago and the nausea is horrendous! I had my bloods done on Thurs, and depending on the results I am supposed to titrate up to 100mg, but unless this settles, I don’t think I can take a higher dose. I am trying to persevere in the hope it improves my crohns in the long run but I’m struggling! Anyone else experienced this, or have any advice? Thank you

[Valbaty54]

I was on Aza for 4 years and used to take it in the evening immediately after my meal. That worked well for me - nausea was never a problem. When do you take yours?

[Bigchiefld in reply to Valbaty54]

Yes I take mine in the evening after food as well. Thank you for replying. I will ring my IBD nurse tomorrow.

[Customerservice]

I was on azathioprine for a while without nausea then the nausea kicked in to the point I was somwtimes sick. Spoke to IBD Nurse got changed to mercaptopurine and all ok at the moment.

[markot]

Azathioprine was terrible for me with nausea, liver enzymes to the roof. We had to switch to mercaptopurine and so far good.