opemrazole gastro capsules

[Tonnross]

having cll and issues I have been on omeprazole for years due to the amount of meds Iam on. However recently been told that these are not for long term use. Anybody used them or have information. Iam in year 12 cll but it’s sepsis that’s causing me havoc and totally knackered all the time lol rant over

[Rando21]

I’ve heard the same but heard conflicting info about risks. It helps me a lot too so I’ve wondered about this myself.

[Hilomom]

I took it for years, until it stopped being effective.

[Suzie42]

I was on it for 4 years when suddenly it didn't work snd reflux got so much worse. I've tried other medication but nothing has worked. I've got to have an Endoscopy now to find out what is going on. It's frightening as all the medication I take has obviously impacted my stomach etc. I didn't have hardly any problems before I started taking Omeprazole, my gp gave it to me as I was having asprin daily for my heart.

[Tonnross in reply to Suzie42]

aspirin comes in different forms. do you take it under your tongue.

[Suzie42 in reply to Tonnross]

No it's gastro resistant and I swallow with water

[LeoPa]

I took omeprazole for a few days before I stopped, because it caused stomach pain to me. Back in those days I had acid reflux. Not because of medications but because of my crappy diet. I cleaned up the diet and acid reflux went away. Never had it ever since.

[Suzie42 in reply to LeoPa]

I've got a crappy diet, but the meds have changed my taste buds and cannot stomach eating healthy foods. It's a disaster, the only plus side is I cannot stand alcohol anymore

[LeoPa in reply to Suzie42]

What do you mean? Food isn't about taste buds but nutrition. Nutritious -eat, crap-don't eat. The rest is just willpower 🙂 Having said that, taste buds can be rewired. I love my meat and eggs 💞

[Suzie42 in reply to LeoPa]

Medication has affected my taste buds and so when I say go to eat an egg I will want to vomit.....the smell of the food makes me really nauseous. Food I used to love, fish, veg, potatoes, cheese sometimes I cannot eat at times. It is not nice and willpower doesn't come into it at all. I have anti sickness tablets to help. I used to eat fish and mainly chicken, I now like lamb but if I eat it after an hour I feel really sick.

[LeoPa in reply to Suzie42]

Wow, sorry about that.

[Accordion]

I have also taken ezomeprazol for years. Take it first thing in the morning, before I take any other pill. During the day I then try to spread out the different medicines, for heart and CLL and ITP (among them aspirine and acyklovir). Hopefully that will keep my stomach happy. I never knew ezomeprazole could lose its effectiveness, that was new….

[Tonnross in reply to Accordion]

Thanks, all info is helpful

[Dragonfly2007]

Hi Ton Ross, I'm on them long term. As I have just started treatment with ibrutinib I did some searches to see if it was ok although the pharmacist didn't comment when she saw it on my list. Whilst this link doesn't answer your question I thought it might be of interest.

PubMed says: The pH-altering agent omeprazole affects rate but not the extent of ibrutinib exposure. This drug-interaction study evaluated the effect of omeprazole, a proton-pump inhibitor, on ibrutinib's pharmacokinetics (PK) in healthy participants.Conclusions: The decrease in Cmax without a corresponding decrease in AUC by omeprazole was not clinically relevant for ibrutinib's bioavailability. No dose adjustments are recommended during ibrutinib's co-administration with omeprazole or other pH-altering agents.

I take mine 3 hours before the ibrutinib.

[Tonnross in reply to Dragonfly2007]

Thanks all helps but it seems we are all different in how it works or not

[Phil4-13]

Tonnross, I was put on protonix(pantoprazole), one daily. Into the 4th month I noticed my calves felt "fuzzy" and my legs felt wobbly. I stopped it. I have had omeprazole for a long time, but only took it before a meal that might have a "surprise spice". I now rely on famotidine in those instances. 🙂 Sandra

[Tonnross in reply to Phil4-13]

Cheer seems it’s so different for everybody

[MikeHoff]

I have CLL since 2010. 6 years W&W then 6 years on Imvruvicac(Ibrutinib) and currently MRD Undetectable. In 2006(prior to CLL diagnosis,) I had gastric sleeve procedure for weight loss and after losing 100 lbs I was prescribed daily regimen of supplements to make up for those missed due to reduced diet and also 40 mg Omeprazole daily prophylactic forever in order to avoid ulcer or other stomach issues which would be difficult to treat due to reduced stomach size. I have had no problems with it and my GO and CLL care team are all aware and fine with it.