Latest bloods

[cartwheels]

Latest bloods not that great.Ibrutinib nearly 8 years, although been slipping last two .

HB bloods 142

WBC 34.4

Neutrophils 3.2

Lymphocytes 29.4

Platelets 120

CT scan booked and back at the hospital in two weeks

[Hoffy]

sorry to hear that. Prutobrutinib (sp?). might be good. The BTK degrader are supposed to be very good. Brian Koffman of CLL society did a Bispecific antibody and is doing well. Check CLLsociety web site.

Be well,

Hoffy

[Skyshark in reply to Hoffy]

Going off the NICE appraisal start mid April 2025 and late June 2025 deadline for submissions I can't see Pirtobrutinib being approved for regular use by UK NHS until sometime late 2025 or early 2026. It maybe available on compassionate grounds.

nice.org.uk/guidance/indeve...

First line use will be even later unless the submission is discontinued.

Currently approved is Venetoclax + Rituximab for 2 years.

Or find a trial.

[Hoffy in reply to Skyshark]

Maybe there are some clinical trials.

Be well,

Hoffy