new info on booster shots affecting the immune system in a negative way and an alternative shot is available

[craterlake]

hi everyone . fire season officially over in southern oregon today which is a relief ... i am still doing well on O+V ..🙂. started a year ago after major calquence fail........here is a link to a recent, short video from the U.K.. i would really appreciate it if some of you very learned folks would please watch it and comment on how this information can affect us if we chose to avail ourselves of this vaccine .. thanks ... blessings , james youtube.com/watch?v=Bykt4ey...(Not working as expected?)

[Phiphiminux]

Hi James , Some Lymphomas reactions :

Non-Hodgkin Lymphoma Developed Shortly after mRNA COVID-19 Vaccination: Report of a Case and Review of the Literature

pubmed.ncbi.nlm.nih.gov/366...

[AussieNeil Partner Administrator in reply to Phiphiminux]

For those who don't have the time to read what you've referenced, it is rightly bringing to attention several cases of lymphoma that have developed in people who have had COVID-19 vaccinations, but we won't know without more research whether there a cause and effect here, or it's simply coincidental. As what you've shared concludes "We are aware that the link between COVID-19 vaccination and lymphoma most likely is a chance phenomenon, and that COVID-19 vaccines represent very efficient products for many people around the world. However, we believe that clinical events, even if only temporally associated with novel treatments or novel vaccines, should be reported for the benefit of the patients and the scientific community. "

Neil

[spi3 in reply to AussieNeil]

December 2021 - THAT was what I believed and I told all the Dr's (even the ones at Dana Farber) when my husband was dying when his kidneys were shutting down 21 days after his 4th COVID shot

[AussieNeil Partner Administrator in reply to spi3]

That experience must have been very frightening for you and your husband, who I I'm pleased to note is now blood MRD negative. Your husband has an excellent CLL doctor and Dana Farber has a very good reputation for managing CLL, so what test results did your husband have around that time and how did his doctors react? Acute lymphoma development in CLL (Richter's Transformation) is curable, but challenging to treat.

Neil

[spi3 in reply to AussieNeil]

Ty so much for understanding and the local hospital informed my husband he had Ritchter! - well they sent us to Dr Davids at Dana Farber and he redid the tests and they had discovered that it was the wrong diagnosis and my hubby had CLL. We had an angel at the previous local hospital that referred us. Also I heard our local hospital has referred several folks to Dana-Farber since.

[craterlake in reply to Phiphiminux]

Interesting .. thanks Phiphiminux ..

[AussieNeil Partner Administrator]

Hi James,

I'd be cautious about what's been shared in this video because:

1. During the pandemic, Dr (PhD in nursing education) John Campbell discovered he could do very well financially from his YouTube channel by catering to those distrustful of COVID-19 vaccinations, in particular mRNA vaccines. Many of the claims subsequently made in his videos have been debunked by people more knowledgeable about the subject matter. See my post and replies here:

healthunlocked.com/cllsuppo...

2. Professor Dalgleish may have a conflict of interest per en.wikipedia.org/wiki/Angus... "Dalgleish is on the scientific advisory board of Immodulon, and has stock options in Immunor AS, a disclosure he made in order to have his research work published."

Professor Dalgleish's claims are in respect to the class switching behaviour of plasma cells, which initially produce IgM, before switching to other Ig types, including various IgG subtypes, including IgG4. As the abstract of this article in Science Immunology from February 2023 Is it bad, is it good, or is IgG4 just misunderstood? science.org/doi/10.1126/sci... notes "Repeated doses of mRNA vaccines for COVID-19 result in increased proportions of anti-spike antibodies of the IgG4 subclass, which are known to neutralize well and to form mixed immune complexes with IgG1 but, in a pure form, might be less effective than IgG1 or IgG3 antibodies in facilitating opsonization by phagocytes, complement fixation, and NK cell–dependent elimination of infected cells ."

Further in the paper, the author proposes a hypothetical scenario and recommend caution thus; "IgG4 antibodies constitute a relatively small proportion of total anti-spike IgG after vaccination, will also likely be of higher affinity because they emerge late, and can form mixed immune complexes with IgG1; in practical terms, they are unlikely to compromise immunity in vaccinated patients at this time.

Nonetheless, on the basis of the results of the studies discussed here and other theoretical considerations, future clinical studies need to evaluate the effectiveness of temporal spreading out of mRNA vaccine boosts—possibly no more than once a year."

Also, as that article concludes, "Hybrid immunity, as generated by breakthrough infections after vaccination, can also induce anti-spike IgG4 (1), so there is a need for ongoing evaluation and possibly tweaking of mRNA vaccination strategies going forward."

So while we obviously need more research, reducing our risk of actual COVID-19 infections would also be prudent.

Neil

[craterlake in reply to AussieNeil]

as always thanks AussieNeil for checking this out .. i am actually more interested in the skin cancer effect of CLL or the treatments then any negative effect mRNA vaccines may have on leukemia patients ..its a controversial vaccine at best ...it does NOT meet the standard definition of a vaccine ... the Venetoclax is definitely having an effect on my skin ... all my oncologist said was , oh yes CLL patients are prone to skin cancer ..my teeth are also rotting away .. under my crowns .. i have not had a tooth pulled in decades .. i have an infection in another one of my teeth and need it pulled asap .. i had one pulled last year while on calquence . i am wondering if this vaccine dr. dalgleish uses would be helpful with the potential skin cancer and other pathogens .,,,,. infections etc. .. james

[AussieNeil Partner Administrator in reply to craterlake]

We'll have to wait for the results of the clinical trials,

[craterlake in reply to AussieNeil]

Good morning Neil .... i just did some investigation into dr.. campbell .. he has almost 3 million followers on youtube and has had an astounding 692 million views of his presentations .. pretty impressive but meaningless as far as credability goes ... he does have a disclaimer about any info he shares during his programs which i assume most of them have to cover themselves from lawsuits or whatever ... i have gotten most of my medical info from an actual Dr. who you can view on MedCram ... for 2 reasons . #1 ; Dr. Roger Seheult gives health lectures that qualify for credits for continuing education for health professionals .. he was also one of the frontline doctors taking care of critically ill covid patients .. so he has had on the job training as well as being a very well respected professional and # 2 because he is a member of the same denomination as i am the Seventh Day Adventist church .. over the years i have come to trust their medical info more the many others ... especially in the area of using lifestyle changes to reverse the effects of diabetes and heart disease , but this forum is invaluable for cutting edge info about our leukemia disease .. so thanks again for everyone who contributes .here ... hope you are continuing to do well .... blessings , james

[AussieNeil Partner Administrator in reply to craterlake]

Hi James,

You are right about the number of followers not being a means by which you can assess credibility. Per en.wikipedia.org/wiki/John_... "John Lorimer Campbell is an English YouTuber and retired nurse educator known for his videos about the COVID-19 pandemic. Initially, the videos received praise, but they later veered into misinformation.[2] He has been criticised for suggesting COVID-19 deaths have been over-counted, repeating false claims about the use of ivermectin as a COVID-19 treatment, and providing misleading commentary about the safety of COVID-19 vaccines."

Dr Campbell used his experiences in nurse education to build up his YouTube following through providing easily understandable explanations of medical topics. He provided some very good educational material to his growing on-line followers, but then his focus changed as you'll see from the rest of the Wikipedia article. He actually invited Dr Oliver as a guest one of his videos, but refused to correct errors she later became concerned about and blocked her on X, formerly Twitter. She has since documented evidence multiple times from his own videos showing how he has actually given medical training and advice on vaccinations, counter to what he is now claiming in his more recent videos. You'll see that what I've captured over the years in my replies and additions to my post warning about his content confirms what's recorded in his Wikipedia entry healthunlocked.com/cllsuppo...

Neil

[craterlake in reply to AussieNeil]

Good job , thanks 👍

[TruthJunkie in reply to AussieNeil]

Wow!

[MovingForward4423]

This is one person making comments on assumptions that are being made. It’s the same with heart attacks, many people have heart attacks each day but it must be the vaccine if they had that recently. I do not listen to any of these people, I listen to my CLL specialist who saved my life.

[craterlake in reply to MovingForward4423]

yes indeed . thats what makes this forum priceless . 🙂

[LeoPa]

If CLL is exhausting our T cells and frequent boosters exhaust them more, then I am glad I only had one booster initially. and no more. Because no matter the details, how could T cell exhaustion be a good thing?

[FloridaGal2 in reply to LeoPa]

Same here...1

[Vlaminck in reply to LeoPa]

Feel ignorant, but where did you get that CLL exhausts T cells? Or is it an assumption because T cells must do more, given defective B cells? Thanks

[LeoPa in reply to Vlaminck]

It's been frequently discussed here on this site.

[craterlake in reply to LeoPa]

good point ...!!!

but we don't exactly know how our own individual T-Cells will respond to anything till we get it .. not to reassuring for us CLL patients ...

[Vlaminck]

Okay, don't think I've gone over the edge, and most of us in US believe RFK to be a bit touched in the head. Nonetheless, I like to read what "the other side" is saying, and I read the part of his book (in the free sample portion on ebooks) about the apparent slander of Ivermectin with lots of documentation (they did this, according to book, because they couldn't get Emergency Authorization for vaccines they were working on if there was an effective treatment) and came away feeling a bit less trustful of CDC, AMA, Fauci, everything about this -- and yes, I have had 4 vaccinations, 3 moderna, 1 Pfeizer. But think I'll hold up on more. By the way, according to this, a possible reason for surprisingly low incidence of Covid in Africa is because they often take ivermectin due to frequent worm infestation. Lot of mystery for me. (Politically, I hold my nose re Kennedy--too much of a kook)

[AussieNeil Partner Administrator in reply to Vlaminck]

The major difference between most counties in Africa and the developed world is the significantly lower median average African population age. When COVID-19 deaths are mostly in the 50+ age bracket, you are immediately going to have a difference in reported fatality rates. The other big issue is what's reported. African countries generally don't have in place good testing and reporting systems for cause of death.

Neil

[Vlaminck in reply to AussieNeil]

good points

[Vlaminck]

insofar as this video focuses on Tcells versus antibodies, yall might find this interesting about AHCC, which seems, according to this article, to increase CD4 and CD8 (both of which I understand to be positive but is otherwise over my head) as well as NK cells. 2019 article (conflict of interests are given as: Insoo Kang received unrestricted research funding from Amino Up Co., Ltd., Sapporo, Japan, the manufacturer of AHCC® that was discussed in this work, and is a consultant of Amino Up Co., Ltd. Takahiro Maeda, Hiroshi Nishioka, and Fujii Hajime are employees of Amino Up Co., Ltd.): Insoo Kang received unrestricted research funding from Amino Up Co., Ltd., Sapporo, Japan, the manufacturer of AHCC® that was discussed in this work, and is a consultant of Amino Up Co., Ltd. Takahiro Maeda, Hiroshi Nishioka, and Fujii Hajime are employees of Amino Up Co., Ltd.)

ncbi.nlm.nih.gov/pmc/articl...

[Vlaminck]

Wouldn't this apply to all vaccines, since it is the problem of antibodies, not a problem of the mRNA vaccine system? Just had flu vaccine!

[Spike62]

Wow. The very anatomy of a hit job on Dr. Campbell with "misinformation" quotes from Wikipedia, the fact that Campbell could be deriving some income from his YouTube videos, and (with a click) BBC videos of that news organization's rather contrived version of "Bill Nye the Science Gal" "debunking" out of context Campbell clips, serving as judge and jury...... sheesh....Nah, I think forgo the media airbrushing upon which trillions of advertising, grant, endowment and administration dollars depend (not to mention liability), and settle for transparent, peer-reviewed studies from across the globe which is what Campbell presents daily........PS - He gives the intellectual property of his Biology textbooks away in PDF form for free.

[AussieNeil Partner Administrator in reply to Spike62]

Unfortunately, if you look at the videos Dr Oliver has done examining Dr Campbell's, claims, you'll find that she has collected plenty of examples where Dr Campbell has done a "hit job" on his later video content from what he has presented in his earlier videos. That includes ignoring or even countering what he has presented previously where he took the time to explain his scientific reasonings. Sadly, he is now directly contradicting himself regularly.

Neil

[jonathan7176 in reply to AussieNeil]

I tend to file him in the same box as Russell Brand. An anti-establishment kind of guy who just happens to be bankrolled and amplified by .... the establishment.

[SurviveOr]

Very interesting. Most informative.

[craterlake in reply to SurviveOr]

👍

[country76]

Very interesting thank you

[craterlake in reply to country76]

👍

[MovingForward4423]

Here is a great tip! Stop reading social media, in fact come off it altogether. There is so much noise you will never identify the signal from that noise.

[craterlake in reply to MovingForward4423]

thanks for the tip but i don't read social media except to keep in touch with my nephew in the philippines .