BLOOD PRESSURE PROBLEMS: Does anyone have... - CLL Support

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BLOOD PRESSURE PROBLEMS

studi profile image
6 Replies

Does anyone have trouble taking imbruvica in relation to high blood pressure.We know that this medication bumps up blood pressure a lot

If anyone is suffering from high blood pressure,what do you take to control it.

I had no blood pressure until I started taking imbruvica.

Amy help would be greatly appreciated

Thanks to everyone for such a wonderful community.The first email I read every morning is health unlocked

Thanks once again

Trafford.

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studi profile image
studi
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6 Replies
cajunjeff profile image
cajunjeff

Ibrutinib raised my blood pressure. I took amlodipine to treat it which worked at first. I eventually added valsartan and it worked.

After a few years on ibrutinib I asked my doctor to switch me to Acalabrutinib, which supposedly has less risk of cardiotoxicity.

I’m now on acalabrutinib, but still taking bp meds. I would rather not be on any meds, for Cll, my bp, or otherwise.

But I have cancer and it is what it is. Every time I feel sorry for myself for taking meds I hate, I have to remind myself how much harsher treatments can be for other cancers and how fortunate I am to be treating my Cll and bp with a few oral meds with minimal side effects.

If you have access to acalabrutinib, it’s worth a discussion with your doctor about a switch. Acalabrutinib does appear, on average, to carry less risk of side effects than ibrutinib.

Ibrutinib is still a miracle drug fiord some of us and many people do very well on it. It does appear to raise bp though in a significant number of users.

studi profile image
studi in reply tocajunjeff

thanks Cajunjess I have just spoken to my doctor and he has also prescribed the same med,so hope it works for me as it has you you

Thanks once again,

Trafford

hhk50 profile image
hhk50

The ibrutinib raised my BP by around 20 points - just enough to put it into the borderline category but then I had one or two short episodes of Atrial fibrilation. So they sent me to a cardiologist/oncologist who prescribed a very low dose (25 mg/day) of beta blocker called Metoprolol to bring the BP back to where it historically had been. That did the trick.

I was reluctant to take the BP medicine but his philosophy is that if you have a cancer medicine that's working well, it's easier to manage the BP than to switch from Ibrutinib to Acalabrutinib. So far, he's right.

DawnRedwood profile image
DawnRedwood in reply tohhk50

My BP went up too on Imbruvica. I've been taking 25 mg. of Losartan and it's working for me. ALSO, I have gained weight so I don't know which caused the higher BP, weight or the drug.......little of both?

hhk50 profile image
hhk50 in reply toDawnRedwood

I've done some support group research and it seems like Imbruvica can put an extra 10 pounds on you. I don't want to do too much research because I'm happy with that explanation of why I've chubbed up a bit in the past five years.

DawnRedwood profile image
DawnRedwood in reply tohhk50

HA!!! I have too.........and I'd rather blame Imbruvica than the home made ice cream we make and the fact that I like to bake pies, cakes, cookies, etc. I just know it couldn't be that!!!

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