platelets down to 118: was in remission for a... - CLL Support

CLL Support

22,370 members38,481 posts

platelets down to 118

CM19 profile image
CM19
5 Replies

was in remission for a few year after venetoclax and retuximab combo. Platelets are down again and thinking the cll is resurfacing.

anyone go back on venetoclax after a few years? Any luck?

thank you.

Written by
CM19 profile image
CM19
To view profiles and participate in discussions please or .
Read more about...
5 Replies
AussieNeil profile image
AussieNeilAdministrator

Hi CM19,

You haven't posted previously, so I haven't any baseline info to see where you are coming from. 118 is an adequate platelet count and platelet counts can bounce around. I suggest waiting for your next set of blood test results before becoming concerned, particularlyif that's the only symptom you have.

Neil

CM19 profile image
CM19 in reply to AussieNeil

thank you! All other blood work appears normal at this time. Trend maybe going in the direction of treatment again soon but seeing dr and will be able to get a game plan together if that's the case. It can just get a little overwhelming at times.

Thank you again!

cajunjeff profile image
cajunjeff

I’ve not paused venetoclax and got back on it. But in the back of head, my memory fading with age, I remember reading somewhere that people who stop ibrutinib or venetoclax not due to resistance, can rechallenge with the same drug with success.

I know without a citation, that’s probably not too helpful. But it’s reasonable to think that if someone’s Cll comes back, and they didn’t stop the med due to resistance, that they ought to be able to rechallenge with the same med.

I think it will depend on the person and how stable or unstable their Cll is. But I do think, from what I read that, those people who stop venetoclax not due to resistance ought to be able to get back on it. For how long? No one knows because it’s such a new drug. We do know that resistance is an issue with most all Cll drugs and the degree of resistance relates to whether our Cll is slow moving, aggressive or somewhere in between.

CM19 profile image
CM19 in reply to cajunjeff

thank you! I hope venetoclax can be used again if and when treatment is needed again.

Thank you!!

DTSUPP profile image
DTSUPP

My husband just came off the venetoclax and I do remember his oncologist saying that it was an option in the future. As other commenters have stated, I would think that it would depend on any changes in your disease and also, if there are possibly better options.

You may also like...

Low platelets 54 down from 72

have a low platelet count and have to reduce venetoclax from 400 to 300 daily. Has anyone else had...

Worried Lymphocyte Count Up Platelets down

can anyone advise on my latest FBC. My Lymphocyte count has gone from 27.72 to 42.86 and Platelets...

WBC going way down/platelets/lymphocytes way up!

up about 20% and my platelets about 150 more! Anyone have any experience with any of these...

low platelets and venetoclax

have been on venetoclax for 3 months and only my platelet count is dropping. Has anyone had the same

Urgent question: low platelets

because his platelets are down to 6 (normal being 150 to 400). He is having platelets every few...