Venetoclax - Morning vs Night: Has anyone's... - CLL Support

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Venetoclax - Morning vs Night

Winegrape profile image
10 Replies

Has anyone's doctor advised the best time to take Venetoclax as far as it working better if taken in the morning vs. night? My doctor said the time doesn't matter as much as consistency in taking it at the same time of day. I only have 2 months left on it and want it to work as effectively as it can before the end of my treatment.

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Winegrape profile image
Winegrape
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10 Replies
SofiaDeo profile image
SofiaDeo

As far as we know, there isn't any data indicating one time is "better" at fighting cancer than another. IMO there are drug-drug interactions that may affect timing, but not just taking veneticlax alone.

Big_Dee profile image
Big_Dee

Hello Winegrape

My doctor said same thing as your doctor, the time doesn't matter as much as consistency in taking it at the same time of day. Blessing.

cllady01 profile image
cllady01Former Volunteer

Some of our members have taken Venetoclax in the morning, and some have switched to the evening because it worked better for them to do so. As your Dr. has said, being consistent is the key.

thb4747 profile image
thb4747

I’ve only been taking Venetoclax since April 2018 but I take my pills at around 9am every day and that’s gone well for me.

Schubert1870 profile image
Schubert1870

I have been taking the 4 Venetoclax pills with breakfast for the past 1 1/2 years, which has been the most convenient time of day for me.

difor29 profile image
difor29

I take 8 Venetoclax pills with breakfast at 9am everyday. I do it in the morning so I don’t forget to take them 🤦🏼‍♀️

larrymarion profile image
larrymarion

Winegrape, this question comes up a frequently in various support groups i'm involved in, as well as my own experience with V over 16 months. Others have noted that the hemocs don't have any data indicating one time of day is better than another. Many advised that the time of day may depend on your side effect profile. Maybe fewer/less serious side effects if the V pills are taken in the evening, but that is strictly anecdotal. My own experience mirrors that of others--I took it in the morning since i didn't have any side effects and it was easier to take the V pills along with my vitamins, etc. so i wouldn't forget. 😀

bayside64 profile image
bayside64

I also have about 2 months left on Venetoclax. I found taking it 6:00-7:00 works really well for me. (PM)

shoshanaz profile image
shoshanaz

I had nausea issues so took it at night with a little food. It still did its work.

casanova profile image
casanova

I agree with the previous comments that consistency is the main thing. I switched from morning to evening due to nausea and diarrhoea with no difference in its effectiveness. I trust all continues to go well for you.

Maureen [UK]

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