CLL and CANABAIS

[Dyba]

CLL and canabais ? I do ,or rather did enjoy having a few beers on a weekend with friends and family . Nothing heavy . Say , achieving, a nice little "buzz". I enjoyed that relaxation and feeling . However I guess that's off the table now. I

am not a canabais user. I hear about chewables that seem to be popular. There are reputable stores in my community . Has anybody made the switch?

[JigFettler Volunteer]

Hi! You may get a better response if you locked your post to the Forum only! Jig

[lankisterguy Volunteer]

Hi Dyba,

-

We have had many discussions about alcohol and CLL. Here is a list of the 170 times alcohol was mentioned in a post: healthunlocked.com/cllsuppo...

-

While some clinical trials restrict alcohol, the consensus of many CLL expert doctors seems to be that patients with good kidney & liver function can consume moderate amounts of alcohol whether or not they are in treatment.

-

Any patient with low EGFR or other out of normal results in their liver and kidney blood test results would be wise to discuss the subject seriously with their hematologist. Many of our current targeted treatments place additional loads on the liver and kidneys, so preserving those carefully may aid longer survival.

-

Len

[AussieNeil Partner Administrator]

In considering switching your 'nice little"buzz"' inducer from alcohol to cannabis, per healthunlocked.com/cllsuppo... "Our findings suggest that the drug might promote homing of lymphoma cells from blood into secondary lymphoid organs where they receive pro-survival signals. Therefore, this cannabinoid compound should be used with caution in patients with indolent leukemic lymphomas."

So in other words, the active ingredients in cannabis could drive CLL cells from the blood, where they are relatively dormant, into the lymph nodes, where they multiply the fastest. If your lymphocyte/white blood cell count dropped after switching from alcohol to cannabis, you might think that your CLL has improved, only for the opposite to be the case.

Neil

[Sumoldbloke in reply to AussieNeil]

That is very interesting and could explain why someone with highly indolent markers and generally good prognosis and slow doubling time and no symptoms could end up with a very enlarged spleen. Hmmm

[Smakwater in reply to AussieNeil]

I believe that I witnessed this firsthand during the clinical trial that I was in. There was no restriction for alcohol or cannabis. I chose not to supplement or add anything to my system that would influence the lab outcomes. My lymph node size returned to normal and I was allowed a BNB measurement. The BNB revealed that I was uMRD at 8 mo's "unofficially", and I was allowed to continue the trial as prescribed.

I interpreted from conversation with those who had used cannabis based products that they had less adverse nausea symptoms from treatment, however at the 8 month evaluation, those who I spoke to having used cannabis products still had enlarged lymph nodes, and due to the continuance criteria, they were required to have additional treatment before being measured for MRD status.

Note: To my knowledge there was no official stating for the cannabis relativity conditions, nor was cannabis determined as the cause, as the lymph node reduction was the measure rather than possible cause observation criteria.

JM

[Pageboy]

No, just still enjoy a couple of glasses at the weekend. It’s ok with the meds I am on, makes me happy to join friends and family, and that’s important too.

[Big_Dee]

Hello Dyba

Good question. I drink a glass of red wine just about every evening and have been doing so for many years before being diagnosed with CLL. I drink the wine for its heart benefit. I can say that I don't get a little buzz.

Alcohol effects your visual nerves coming from eye to brain. You know how your eye ball image is converted 180 degrees to appear right side up in your brain, well your audio nerves do same thing to give your brain meaning of sound from your ears. Audio nerves are also effected by alcohol. I have very poor hearing and too much alcohol greatly reduces my hearing just like it makes your eyes blurry. In my opinion anything that befuddles your brain is going to cause problems for your sensors.