Nitric Oxide Nasal Spray (NONS) ... is this all it is cracked up to be?

[Me2AsWell]

Dear All,

My colleague in India sent me this: prnewswire.co.uk/news-relea...

"Phase 3 trial in India met the key endpoints and demonstrated reduction of viral load of 94% in 24 hours and 99% in 48 hours.

NONS was safe and well tolerated in COVID-19 patients.

Glenmark received manufacturing and marketing approval from India's drug regulator for Nitric Oxide Nasal Spray (NONS) as part of accelerated approval process."

Does anyone have insights on the value/efficacy of NONS?

A NCBI study (just 80 patients) concluded: " Accelerated SARS-CoV-2 clearance with NONS may reduce symptom duration, decrease infectivity period, reduce hospital admissions, and lower disease severity. Consequently, this study could be used as supporting evidence for emergency use of NONS for patients with mild COVID-19 infection.

"ncbi.nlm.nih.gov/pmc/articl...

And the NHS is looking at it: "The first UK clinical trials of a nasal spray proven to kill 99.9% of the coronavirus that causes Covid-19 began on January 11th at Ashford and St Peter’s Hospitals NHS Foundation Trust, in Surrey."

ashfordstpeters.nhs.uk/rese...

Should we be skipping with joy?

[mdsp7]

Looks interesting!

[Justasheet1]

“Last updated May 12, 2021.” This predates Omicron so I hope it’s still effective.

Sounds interesting though.

Jeff

[Phil4-13]

Me2AsWell, I feel like skipping! I sure hope that nasal spray passes all tests with flying colors! 🙂Sandra

[LeoPa]

I hope it's as good as advertised. Where can I buy some OTC? It doesn't seem available yet.

[Me2AsWell in reply to LeoPa]

It is available in India - my office offered to ship me some. But I am not sure how happy the UK authorities would be too happy until it is approved here.

[LeoPa in reply to Me2AsWell]

Lucky you! The happiness and well-being of the authorities is important, it's right behind our own 😀

[Drew458 in reply to LeoPa]

It's been on the world market for about a year now. Product name is Enovid.

israelpharm.com/enovid-anti...

[LeoPa in reply to Drew458]

Thank you 🙂

[oryoki]

The body naturally produces NO.

By controlled breathing and humming as described in the linked videos you can naturally produce NO at a level 200X the normal production of the body.

A cursory search did not reveal how much more NO is applied with this spray than normal body production.

The controlled breathing with humming is available right now, no need to go to the pharmacy, no need to spend money, no need to wait for supplies to meet demand. You can start immediately and receive the benefits of increased NO in the nasal passages and into the body.

No clinical studies have shown the efficacy of humming as it’s free and there is no monetary reward for doing so. You can make your own judgements and use humming as a solution or as a fill in until you can get your hands on this product. Or both.

youtube.com/watch?v=AiwrtgW...(Not working as expected?)

youtube.com/watch?v=6v-nTRL...(Not working as expected?)

[oryoki in reply to oryoki]

Seems there was a problem with a couple of the links, repeated here.

youtube.com/watch?v=bis1gvj...(Not working as expected?)

youtube.com/watch?v=AiwrtgW...(Not working as expected?)

[oryoki in reply to oryoki]

And again

youtube.com/watch?v=bis1gvj...(Not working as expected?)