UK medicines regulator approves Pfizer’s ‘life... - CLL Support

CLL Support

23,324 members40,026 posts

UK medicines regulator approves Pfizer’s ‘life-saving’ Covid pill

Harvist profile image
7 Replies

"UK regulators have approved Pfizer’s “life-saving” antiviral drug Paxlovid, which boasts nearly 90% success in preventing severe illness among vulnerable adults if taken soon after becoming infected with Covid-19.

The agency said Paxlovid was most effective when taken during the early stages of a Covid infection, and recommended it was used within five days of a patient’s first symptoms. The approval is for patients aged 18 and over with at least one risk factor for developing severe illness, such as obesity or diabetes, or being over 60.

“We now have a further antiviral medicine for the treatment of Covid-19 that can be taken by mouth rather than administered intravenously. This means it can be administered outside a hospital setting, before Covid-19 has progressed to a severe stage.

“I hope the announcement gives reassurance to those particularly vulnerable to Covid-19, for whom this treatment has been approved. For these individuals, this treatment could be life-saving.”

Pfizer has said the drug showed near 90% efficacy in preventing hospitalisations and deaths in high-risk patients, with recent data suggesting the pill was also effective against the Omicron variant.

Before Christmas Pfizer said the UK government had agreed to purchase 2.5m courses of Paxlovid after an earlier purchase of 250,000 doses, conditional on regulatory approval."

Article in the Guardian at 1600 today.

All we need now is a clear route to actually getting it!!!

Written by
Harvist profile image
Harvist
To view profiles and participate in discussions please or .
Read more about...
7 Replies
Eucalyptus22 profile image
Eucalyptus22

I think the clear route to actually getting it will be the biggest hurdle. The government approved antiviral tablets last November but has anyone received any yet or been advised how to get them? When I questioned my GP he knew nothing about any protocols to administer them so I guess it will be months before we get access to these new ones. At least there are reports on this site of successful access to MABs.

Mijoed profile image
Mijoed in reply toEucalyptus22

And the advice, if you test positive and are not contacted within 24 hrs, is to call your GP or 111. My GP also knows nothing about and early treatment options. A sad state of affairs when JCVI and NHS documentation is freely available/distributed, most of us know what is supposed to happen, but the chain stops there.

LeoPa profile image
LeoPa

Our government canceled the monupiravir order and replaced it by paxlovid. They say it should arrive sometime in the first half of 2022. I'm sure we will have plenty of it by the time nobody needs it 😁

Annie1920 profile image
Annie1920

Some health authorities are well advanced eg Bristol and South Gloucester.. This authority had published a pathway document where GPS and hospital medics can check if patients are registered and if not an register eligible ones

remedy.bnssgccg.nhs.uk/covi...

Sadly neighbouring Somerset has nothing.. Even the CMDUs are just proposed so nothing available yet

bennevisplace profile image
bennevisplace

If the reported purchase agreement for 2.5 million doses is true, that's more like it!

The treatment protocol will be similar to that already published for Molnupiravir, except that Paxlovid is two different pills copackaged. I would happily take P, though there are serious contraindications for some.

Septuagenarians will be amused to read that being over 60 is a risk factor!

casanova profile image
casanova

In an ideal world we would all have a pack in our meds cupboard, but a fast, clear access route would be wonderfully reassuring.Maureen UK

francc profile image
francc

Paxlovid, could interfere with ibrutinib.

Not what you're looking for?

You may also like...

Important SARS-CoV-2 and Covid-19 information for Chronic Lymphocytic Leukaemia/CLL patients

This post, prepared in collaboration with        @[52122] , draws together some earlier posts...
CLLerinOz profile image
Administrator

Efficacy of the Molnupiravir antiviral pill - Help!

Thanks to CLLerinOz for giving us an update on the trial results for Molnupiravir...

Molnupiravir: A Pill for COVID Could Be Here Soon

From The People's Pharmacy 1st Oct 2021 and good news for immunocompromised patients like us. "...
Jm954 profile image
Administrator

UK Government announce that supplies of Molnupiravir and Ritonavir against Covid 19 have been secured.

Thousands of vulnerable patients could be taking ground-breaking COVID-19 antivirals this winter...
Jm954 profile image
Administrator

Vaccine candidate was found to be more than 90% effective in preventing COVID-19 in participants without evidence of prior SARS-CoV-2 infect

#CLLSociety Pfizer and BioNTech’s big news this week of a promising novel (not "live") “RNA”...
bkoffman profile image
CLL CURE Hero

Moderation team

See all
CLLerinOz profile image
CLLerinOzAdministrator
AussieNeil profile image
AussieNeilAdministrator
Newdawn profile image
NewdawnAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.