NON RESPONDERS TO SARS COVID 19 Vaccine - CLL Support

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NON RESPONDERS TO SARS COVID 19 Vaccine

JJSI profile image
JJSI
3 Replies

I was diagnosed with CLL and have been on Ibrutinib treatment for over 3 years, doing fairly well. My second shot of moderna vaccine was two months ago and I decided to check my inmunological response by antispike SARS COV 19 test, the result was 0.1 (no response).

Has there been any studies or trials of using a third dose of any mRNA vaccine or an other type of vaccine , if so what where there any results.

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JJSI profile image
JJSI
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3 Replies

Sorry to hear that, we all will be wondering until we get tested

gardening-girl profile image
gardening-girl

JJSI, There are a couple of clinical trials testing booster vaccines for SARS-CoV-2.

The Phase I Clinical Trial of Booster Vaccination of Adenovirus Type-5 Vectored COVID-19 Vaccine

clinicaltrials.gov/ct2/show...

Moderna Announces First Participants Dosed in Study Evaluating COVID-19 Booster Vaccine Candidates

clinicaltrials.gov/ct2/show...

Study to enroll 60 participants previously vaccinated with mRNA-1273 in Phase 2, to evaluate booster vaccine candidates (mRNA-1273.351) against the B.1.351 variant first identified in South Africa

and a second mRNA that is being considered for a booster dose:

First Participants Dosed in Phase 1 Study Evaluating mRNA-1283, Moderna’s Next Generation COVID-19 Vaccine

mRNA-1283 is intended to be evaluated in futures studies for use as a booster dose for previously vaccinated or seropositive as well as in a primary series for seronegative individuals.

investors.modernatx.com/new...

gardening-girl

bennevisplace profile image
bennevisplace in reply to gardening-girl

Interesting, thanks. It would be nice to see a vaccine booster trial in blood cancer patients (we would be excluded from these two). Not much in it for the drug companies though.

A couple of weeks ago the UK government was talking about giving the most vulnerable groups a third shot, maybe of an updated vaccine, in the autumn. I'll believe it when I see it.

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