Acalabrutinib used by NHS

[Research123]

I'm sure someone has written abt this but just in case:

europeanpharmaceuticalrevie...

I know this has been around for a while in the US but nice to see progress all the time in the UK. I think from what I've read you should be able to take this longer than ibrutinib as it has less side-effects.

[Jm954 Administrator]

In case anyone missed it, the information and discussion is here:

healthunlocked.com/cllsuppo...

[Research123 in reply to Jm954]

Thank you! Much clearer although it seems not so great as I thought if you're younger as you probably won't get it.....still it's all progress

[AnneHill in reply to Research123]

I mentioned this drug to a haematologist and was told that it wouldnt be funded at that hospital. This was a few months ago and I will ask my consultant about it next month. Just out of interest.They intend to give me venetaclax next if ibrutinib stops working. It would be good if I didnt have the joint pain. Anne uk

[Catdoe]

I have been on Acalabrutinib for a few days now and it is causing me severe migraines & now sickness . I’m told this will pass after a couple of weeks. Time will tell but I think I preferred ibrutinib

[sllincolorado in reply to Catdoe]

Many have found that a little bit of extra caffeine helps the acala headaches. If the migraines are waking you up in the middle of the night you might take a few extra sips of caffeine late in the day. Not sure about your sickness - if you are nauseous and you are taking it without food, try taking it with food. If you have been taking it with food and you are not feeling well - try without. Both options are okay with this med. Drink plenty of water. Good luck.

[Catdoe in reply to sllincolorado]

Thanks for your reply. Are the migraines normally constant? I don’t normally eat in the mornings so maybe I should try food before tablet, although this morning I felt so sick I couldn’t even eat till afternoon. I love my coffee but switched to decaf thinking that would help but maybe I’ll switch back .

[sllincolorado in reply to Catdoe]

From what I know, the acala headaches usually last a few days to a few months. Just about everyone says caffeine helps. Even the docs suggest it. I might be able to find some links for you. Until I started these types of meds I did not eat in the morning. I was never much of a breakfast eater. I have completely changed how I eat now. I have caffeine, then I start eating - take the pills - and then eat a bit more.

[Catdoe in reply to sllincolorado]

Hi again , I tried proper coffee & toast this morning with much better results 🙂. Thank you so much . Have a great day !