The time has come.

[Coolerjoe]

Well after 25 months the time has come for treatment. WBC is 182.5, HGB 12.4 Lymphocytes 91 Starting a trial at Rutgers cancer institute in about 3 weeks 19 months of cycle waiting to find what arm I will be in.

[gardening-girl]

Wishing you the best! Let us know when you find out which arm you will be on and keep us posted throughout your trial!

gardening girl

[country76]

Me too. Today was my first day of Ibrutinib. Wishing you the best with the trial.

[DMary]

I think I had just finally settled into the idea of CLL when it was time to start treatment. It can be a shock even if you're expecting it. All the best wishes for a smooth process and recovery.

I'll be watching for your progress and updates with interest. Which trial or you enrolled in?

[cajunjeff]

Yo Joe, good luck. What arms do they have in your trial?

[Coolerjoe in reply to cajunjeff]

Imbrutinib Obinutuzimab is one

Imbrutinib Obinutuzimab and Venticlax is the other

[cajunjeff in reply to Coolerjoe]

Wow, that’s a great trial. I am sure they know more than me, but the results of that trial appear predictable.

Basically you have the three new all rock star drugs in one trial. At least in the short term, we already know venetoclax is the most powerful drug of the three. That arm will almost certainly put more people into deeper early remissions.

Ibrutinib and obinutuzimab is a great combo on its own. I wonder what they expect to find out comparing the two combinations.

Venetoclax to me is like the bacon for all the new combinations. You wrap just about anything in bacon and it’s going to taste better.

That said, I wouldn’t be disappointed at all to be in the ibrutinib obinutuzimab arm. People in that arm are going to do great too and still have venetoclax in their back pocket for later.

[Coolerjoe in reply to cajunjeff]

Agreed. That is why we decided to do the trial. Plus who doesn’t like 🥓

[Elizabetha]

Hi Joe, good luck with the treatment. I hope that you get the best arm for you!

Take care and best wishes.

[Saylor2076]

Hi joe

Best wishes for successful treatment!!!!