I was diagnosed with CLL in 2008, with no negative markers on the FISH test. I was deemed to have all the good markers on other tests, CD38 negative, ZAP 70 negative, and good mutational state. However, my WBC has continued its relentless upward trend (now at about 70), In 2012 I developed AIHA, or Auto Immune Hemolytic Anemia. When My hemoglobin went below 10 I was treated with a combo of steroid and Rituxin for four weeks (a once a week infusion). It seemed to help a little for about 2 or 3 months and my hemoglobin now seems again on the way down (10.6 currently).
I am wondering if anyone else has been marginally responsive to Rituxin. If so what can take its place when I need the next round of treatment. I would like to avoid having to do a full blown treatment for CLL (Ibrutinib etc). I have, TG, always felt well and would hate to start taking something that will reduce my sense of well being.
I was wondering if genetic testing might identify a possible drug for me?? Thank you everyone. Elaine