Interesting : I came upon this article this... - CLL Support

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Interesting

Swissnology profile image
6 Replies

I came upon this article this morning news-medical.net/news/20160...

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Swissnology profile image
Swissnology
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AussieNeil profile image
AussieNeilPartnerAdministrator

Good to see some Bloodwise funded research that enabled scientists at the Institute of Cancer Research, London 'to identify for the first time the role that (a specific) area of the genome plays in the formation of this leukaemia. They found that a single letter DNA sequence variation – known as a single nucleotide polymorphism (SNP) - at a specific site in the genome disrupts the activity of a protein called RELA. This protein is involved in a process of controlled cell death that is a key part of the body’s natural defence against disease.'

I wonder if some of the funds raised by Hidden and members supporting him contributed to this research?

Neil

Cllcanada profile image
CllcanadaTop Poster CURE Hero in reply toAussieNeil

Here is the full paper ...

cell.com/cell-reports/pdf/S...

virdieblue profile image
virdieblue

Isn't that what Venetoclax targets?

Virginia

Cllcanada profile image
CllcanadaTop Poster CURE Hero in reply tovirdieblue

No VENCLEXTA (Venetoclax ABT-199) targets BCL2

Lots here ...

biooncology.com/pathways/bc...

cllady01 profile image
cllady01Former Volunteer

My brain is either like Swiss Cheese or a sieve, now. Overloaded with info that may sometime be useful to know. Perhaps tomorrow, I will be able to digest some of this.

Is this talking about killer cells or proteins on killer cells. Man, and I thought higher math was difficult.

Cllcanada profile image
CllcanadaTop Poster CURE Hero

Good article on this topic... from ICR... understand how CLL may work

Might be the same article that starts this thread... but this is a fundamentally import breakthrough... it is worth recycling... ♻️

icr.ac.uk/news-archive/rese...

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