Husband returning to treatment

[LAinNYC]

After 10 months of well-managed anemia (PRCA), using cyclosporine, my husband's WBC is rising, and he's likely to need CLL treatment again (he had 2 rounds of FCR 2 years ago). We're looking for CLL treatment options that will be less likely to trigger the anemia/blood transfusions.

[AussieNeil Administrator]

Good to hear that Lars has had 10 months of well managed anaemia after a pretty rough period for you both a year ago. Has Lars had any treatment recommendations? Thankfully that cyclosporine has bought him time for more CLL drug approvals in the USA and there may also be some trials that Lars may qualify for.

Neil

[LAinNYC in reply to AussieNeil]

We're going to a PRCA specialist on Friday, and hope his recommendation matches what the CLL specialist tells us next week. In the meantime, I'm trying to gather information about the available CLL treatments that may be less hammering to his marrow than FCR; the info about which ones can be taken along with cyclosporine is probably too technical for me to gather as a layperson...

[Cllcanada Top Poster CURE Hero in reply to LAinNYC]

I would look at ibrutinib, but there can be cytopenias... perhaps a rituxan monotherapy or Gazyva and chlorambucil...

[MsLockYourPosts Passed Volunteer]

I

Are you in the U.S.? If so, if Gazyva looks like a possibility ask, also, about losing the chlorambucil to reduce toxicity. My doctor did, as did a friend's. Both doctors have been involved with the treatment since its early trial days.

Pat

[LAinNYC]

Yes, we are in the U.S.