MYC survival protein a potential new target for many cancers including many leukaemias and lymphomas

[AussieNeil]

In some more Australian research, Walter and Eliza Hall Institute researchers have discovered a promising strategy for treating cancers that are caused by one of the most common cancer-causing changes in cells.

The discovery offers hope for treating many types of cancer that are driven to grow and spread through the actions of a cancer-causing protein called MYC.

Up to 70 per cent of human cancers, including many leukaemias and lymphomas, have unusually high levels of MYC, which causes cancerous changes in cells by forcing them into abnormally rapid growth.

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The research was supported by the Kay Kendall Leukaemia Fund, the Leukaemia Foundation of Australia, the Leukemia and Lymphoma Society (US), the European Molecular Biology Organization (EMBO), the German Research Council, Cancer Research UK, the Australian National Health and Medical Research Council and the Victorian Government.

wehi.edu.au/site/latest_new...

Includes a brief video of Dr Gemma Kelly, explaining this research

There has been at least one previous attempt to treat CLL by disabling the MCL-1 protein as reported in this 2011 paper from researchers at the M. D. Anderson Cancer Center

bloodjournal.hematologylibr...

One of the authors is William Wierda, who will be familiar to many of us.

Neil

[jangreen]

The more research the more promise. Best wishes