Sequencing in hematological malignancies

Sequencing in hematological malignancies

A fascintating look beyond FISH tests and how Whole-Genome Sequencing and newly discovered genes like NOTCH1 will begin to translate into new and more individualized treatments...

'Next-generation sequencing has led to a revolution in the study of hematological malignancies with a substantial number of publications and discoveries in the last few years. Significant discoveries associated with disease diagnosis, risk stratification, clonal evolution and therapeutic intervention have been generated by this powerful technology.

As part of the post-genomic era, sequencing analysis will likely become part of routine clinical testing and the challenge will ultimately be successfully transitioning from gene discovery to preventive and therapeutic intervention as part of individualized medicine strategies.'

Full Paper in Nature Journal Blood Cancer


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